Evidence map›Paper›PMID 31065579›Full record

ArticleData in brief2019

The PsyTAR dataset: From patients generated narratives to a corpus of adverse drug events and effectiveness of psychiatric medications.

Maryam Zolnoori, Kin Wah Fung, Timothy B Patrick, Paul Fontelo, Hadi Kharrazi, Anthony Faiola, Nilay D Shah, Yi Shuan Shirley Wu, Christina E Eldredge, Jake Luo and 5 more

Open access · goldAbstract read
In one paragraph

Article in Data in brief, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 44 citations in OpenAlex.

  1. Article
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  5. A Comprehensive Evaluation of Biomedical Entity Linking Models.Proceedings of the Conference on Empirical Methods in Natural Language Processing. Conference on Empirical Methods in Natural Language Processing · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 9 institutions in 1 country.

Maryam ZolnooriLister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Bethesda, MD, United States.
Kin Wah FungLister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Bethesda, MD, United States.
Timothy B PatrickDepartment of Health Informatics & Administration, University of Wisconsin Milwaukee, Milwaukee, WI, United States.
Paul FonteloLister Hill National Center for Biomedical Communications, National Library of Medicine, National Institutes of Health, Bethesda, MD, United States.
Hadi KharraziDepartment of Health Policy and Management, Johns Hopkins University, Baltimore, MD, United States.
Anthony FaiolaDepartment of Biomedical and Health Information Sciences, University of Illinois at Chicago, Chicago, IL, United States.
Nilay D ShahDepartment of Health Sciences Research, Mayo Clinic, Rochester, MN, United States.
Yi Shuan Shirley WuSchool of Pharmacy, University of Pittsburgh, Pittsburgh, PA, United States.
Christina E EldredgeSchool of Information, University of South Florida, Tampa, FL, United States.
Jake LuoDepartment of Health Informatics & Administration, University of Wisconsin Milwaukee, Milwaukee, WI, United States.
Mike ConwayDepartment of Biomedical Informatics, Utah University, Salt Lake City, UT, United States.
Jiaxi ZhuEmmes Corporation, Rockville, MD, United States.
Soo Kyung ParkDepartment of Epidemiology, Johns Hopkins University, Baltimore, MD, United States.
Kelly XuSchool of Pharmacy, University of Pittsburgh, Pittsburgh, PA, United States.
Hamideh MoayyedCollege of Letters and Science, University of Wisconsin Milwaukee, WI, United States.
National Institutes of Health · USUniversity of Wisconsin–Milwaukee · USJohns Hopkins University · USUniversity of Pittsburgh · USEmmes (United States) · USMayo Clinic in Florida · USUniversity of Illinois Chicago · USUniversity of South Florida · USUniversity of Utah · US

Funding

Yale-Mayo FDA Center for Excellence in Regulatory Science and InnovationU01FD005938 · FDA · YALE UNIVERSITY · PI Joseph Solomon Ross · 2016 to 2026
$25.4M
Clinical and Informatics Research in Medical TerminologiesZIALM010013 · NLM · NATIONAL LIBRARY OF MEDICINE · PI FUNG, KIN WAH · 2018 to 2020
$1.6M
FDA HHS U01 FD005938
6 · The paper itself

Abstract

The "Psychiatric Treatment Adverse Reactions" (PsyTAR) dataset contains patients' expression of effectiveness and adverse drug events associated with psychiatric medications. The PsyTAR was generated in four phases. In the first phase, a sample of 891 drugs reviews posted by patients on an online healthcare forum, "askapatient.com", was collected for four psychiatric drugs: Zoloft, Lexapro, Cymbalta, and Effexor XR. For each drug review, patient demographic information, duration of treatment, and satisfaction with the drugs were reported. In the second phase, sentence classification, drug reviews were split to 6009 sentences, and each sentence was labeled for the presence of Adverse Drug Reaction (ADR), Withdrawal Symptoms (WDs), Sign/Symptoms/Illness (SSIs), Drug Indications (DIs), Drug Effectiveness (EF), Drug Infectiveness (INF), and Others (not applicable). In the third phases, entities including ADRs (4813 mentions), WDs (590 mentions), SSIs (1219 mentions), and DIs (792 mentions) were identified and extracted from the sentences. In the four phases, all the identified entities were mapped to the corresponding UMLS Metathesaurus concepts (916) and SNOMED CT concepts (755). In this phase, qualifiers representing severity and persistency of ADRs, WDs, SSIs, and DIs (e.g., mild, short term) were identified. All sentences and identified entities were linked to the original post using IDs (e.g., Zoloft.1, Effexor.29, Cymbalta.31). The PsyTAR dataset can be accessed via Online Supplement #1 under the CC BY 4.0 Data license. The updated versions of the dataset would also be accessible in https://sites.google.com/view/pharmacovigilanceinpsychiatry/home.

Identifiers

PMID31065579
PMCPMC6495095
OpenAlexW2921264916

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.