Evidence map›Paper›PMID 31065492›Full record

Review3 Biotech2019

Plant defensins: types, mechanism of action and prospects of genetic engineering for enhanced disease resistance in plants.

Raham Sher Khan, Aneela Iqbal, Radia Malak, Kashmala Shehryar, Syeda Attia, Talaat Ahmed, Mubarak Ali Khan, Muhammad Arif, Masahiro Mii

Open access · greenAbstract readReview
In one paragraph

Review in 3 Biotech, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed, 1 pooled it
9.1field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 1 synthesis or guideline pooled it, 140 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 3 countries.

Raham Sher Khan1Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Aneela Iqbal1Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Radia Malak1Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Kashmala Shehryar1Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Syeda Attia1Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Talaat Ahmed2Department of Biological and Environmental Sciences, College of Arts and Science, Qatar University, Doha, Qatar.
Mubarak Ali Khan1Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Muhammad Arif1Department of Biotechnology, Abdul Wali Khan University Mardan, Mardan, Pakistan.
Masahiro Mii3Center for Environment, Health and Field Sciences, Chiba University Japan, Chiba, Japan.
Abdul Wali Khan University Mardan · PKChiba University · JPQatar University · QA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Natural antimicrobial peptides have been shown as one of the important tools to combat certain pathogens and play important role as a part of innate immune system in plants and, also adaptive immunity in animals. Defensin is one of the antimicrobial peptides with a diverse nature of mechanism against different pathogens like viruses, bacteria and fungi. They have a broad function in humans, vertebrates, invertebrates, insects, and plants. Plant defensins primarily interact with membrane lipids for their biological activity. Several antimicrobial peptides (AMPs) have been overexpressed in plants for enhanced disease protection. The plants defensin peptides have been efficiently employed as an effective strategy for control of diseases in plants. They can be successfully integrated in plants genome along with some other peptide genes in order to produce transgenic crops for enhanced disease resistance. This review summarizes plant defensins, their expression in plants and enhanced disease resistance potential against phytopathogens.

Indexed as

Disease resistanceGenetic engineeringPathogensPlant defensins

Identifiers

PMID31065492
PMCPMC6488698
OpenAlexW2943777116

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.