ArticleBiomedical optics express2018
Complementary use of polarization-sensitive and standard OCT metrics for enhanced intraoperative differentiation of breast cancer.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 40 citations in OpenAlex.
- Polarisation-Sensitive Optical Coherence Tomography for Surgical Margin Evaluation and Diagnosis of Excised Canine Cutaneous and Subcutaneous Tumours.Veterinary and comparative oncology · 2026Article
- Deep UV laser scanning microscopy with integrated 1050 nm spectral-domain optical coherence tomography for multi-contrast tissue imaging.Biomedical optics express · 2025Article
- OCT in Oncology and Precision Medicine: From Nanoparticles to Advanced Technologies and AI.Bioengineering (Basel, Switzerland) · 2025Review
- A co-registration method to validateHeliyon · 2025Article
- Compressed sensing of human breast optical coherence 3-D image volume data using predictive coding.Biomedical optics express · 2023Article
- Development of polarization-sensitive optical coherence tomography imaging platform and metrics to quantify electrostimulation-induced peripheral nerve injuryNeurophotonics · 2023Article
- Longitudinal investigation of a xenograft tumor zebrafish model using polarization-sensitive optical coherence tomography.Scientific reports · 2022Article
- En-face polarization-sensitive optical coherence tomography to characterize early-stage esophageal cancer and determine tumor margin.Biomedical optics express · 2022Article
- Article
- Evaluating optical coherence tomography for surgical margin assessment of canine mammary tumours.Veterinary and comparative oncology · 2021Article
- Rapid non-destructive volumetric tumor yield assessment in fresh lung core needle biopsies using polarization sensitive optical coherence tomography.Biomedical optics express · 2021Article
- Synthetic polarization-sensitive optical coherence tomography by deep learning.NPJ digital medicine · 2021Article
- Compressive sensing for polarization sensitive optical coherence tomography.Journal of physics D: Applied physics · 2021Article
- Differentiation of breast tissue types for surgical margin assessment using machine learning and polarization-sensitive optical coherence tomography.Biomedical optics express · 2021Article
- Computational adaptive optics for polarization-sensitive optical coherence tomography.Optics letters · 2021Article
- Diagnostic Accuracy of Cross-Polarization OCT and OCT-Elastography for Differentiation of Breast Cancer Subtypes: Comparative Study.Diagnostics (Basel, Switzerland) · 2020Article
- Detection of Oral Dysplastic and Early Cancerous Lesions by Polarization-Sensitive Optical Coherence Tomography.Cancers · 2020Article
Corrections and comments
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Authors and funding
12 authors at 2 institutions in 1 country.
Funding
Abstract
We report the development and implementation of an intraoperative polarization-sensitive optical coherence tomography (PS-OCT) system for enhancing breast cancer detection. A total of 3440 PS-OCT images were intraoperatively acquired from 9 human breast specimens diagnosed by H&E histology as healthy fibro-adipose tissue (n = 2), healthy stroma (n = 2), or invasive ductal carcinoma (IDC, n = 5). A standard OCT-based metric (coefficient of variation (CV)) and PS-OCT-based metrics sensitive to biological tissue from birefringence (i.e., retardation and degree of polarization uniformity (DOPU)) were derived from 398 statistically different and independent images selected by correlation coefficient analysis. We found the standard OCT-based metric and PS-OCT-based metrics were complementary for the differentiation of healthy fibro-adipose tissue, healthy stroma, and IDC. While the CV of fibro-adipose tissue was significantly higher (
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Registered trials
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