ArticleBiomedical optics express2018
Characterizing stratum corneum structure, barrier function, and chemical content of human skin with coherent Raman scattering imaging.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
23 citing papers in PubMed, 64 citations in OpenAlex.
- A serum and cream moisturization regimen outperforms separate use in sustaining hydration, reducing TEWL, and balancing surface lipids over an 8-h study.International journal of cosmetic science · 2026Trial
- Understanding the dandruff flare-up: A cascade of measurable and perceptible changes to scalp health.International journal of cosmetic science · 2025Trial
- Design and characterisation of a film-forming emulsion combining enhanced skin permeability with prolonged drug delivery.Biomaterials and biosystems · 2026Article
- Enhancement of the Moisturizing Effect in an Injectable Sodium Hyaluronate Composite Solution by the Addition of Glycine, Alanine, and Proline.Journal of cosmetic dermatology · 2026Article
- Topical 915-3985 MHz Microwave Sweep-Assisted Retention of Nanoemulsified α-Tocopherol for Dermatitis Treatment.AAPS PharmSciTech · 2026Article
- Noninvasive Monitoring of Palmitoyl Hexapeptide-12 in Human Skin Layers: Mechanical Interaction with Skin Components and Its Potential Skincare Benefits.ACS applied bio materials · 2025Article
- A Deep Dive Into the Potential Antiaging Effects of Colla Corii Asini on the Skin: A Comparative Study.Journal of cosmetic dermatology · 2025Article
- Review
- Impact of Skin Decontamination Wipe Solutions on the Percutaneous Absorption of Polycyclic Aromatic Hydrocarbons.Toxics · 2024Article
- Film-Forming, Moisturizing, and Sensory Properties of a Cosmetic Formulation Containing Tara Gum and Brazilian Berry Extracts.AAPS PharmSciTech · 2024Article
- Advances in the transdermal delivery of antiretroviral drugs.SAGE open medicine · 2024Review
- Microneedle-Assisted Transfersomes as a Transdermal Delivery System for Aspirin.Pharmaceutics · 2023Article
- Ultra-High Frequency UltraSound (UHFUS) Assessment of Barrier Function in Moderate-to-Severe Atopic Dermatitis during Dupilumab Treatment.Diagnostics (Basel, Switzerland) · 2023Article
- Enhancing Intradermal Delivery of Lidocaine by Dissolving Microneedles: Comparison between Hyaluronic Acid and Poly(Vinyl Pyrrolidone) Backbone Polymers.Pharmaceutics · 2023Article
- Types of spectroscopy and microscopy techniques for cancer diagnosis: a review.Lasers in medical science · 2022Review
- Review
- Novel Pharmaceutical Strategies for Enhancing Skin Penetration of Biomacromolecules.Pharmaceuticals (Basel, Switzerland) · 2022Review
- Lipid Nanoparticulate Drug Delivery Systems: Recent Advances in the Treatment of Skin Disorders.Pharmaceuticals (Basel, Switzerland) · 2021Review
- Lipid-Polymeric Films: Composition, Production and Applications in Wound Healing and Skin Repair.Pharmaceutics · 2021Review
- The Concept of Advanced Multi-Sensor Monitoring of Human Stress.Sensors (Basel, Switzerland) · 2021Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The most superficial layer of the epidermis, the stratum corneum, plays a crucial role in retaining hydration; if its structure or composition is compromised, dry skin may result as a consequence of poor water retention. Dry skin is typically treated with topical application of humectant agents that attract water into the skin. Corneometry, the industry standard for measuring skin hydration, works by assessing the bulk electrical properties of skin. However, this technique samples a large volume of tissue and thus does not resolve the biochemical changes that occur at the cellular level that may underlie mechanisms of dry skin. These limitations can be addressed using coherent Raman scattering (CRS) microscopy to probe the intrinsic vibrational modes of chemical groups such as lipids and water. In the present study,
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.