ArticleBiomedical optics express2018
Polarization-resolved second harmonic microscopy of skeletal muscle in sepsis.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
8 citing papers in PubMed, 20 citations in OpenAlex.
- Investigating cartilage-related diseases by polarization-resolved second harmonic generation (P-SHG) imaging.APL bioengineering · 2024Article
- Categorization of collagen type I and II blend hydrogel using multipolarization SHG imaging with ResNet regression.Scientific reports · 2023Article
- SEMPAI: a Self-Enhancing Multi-Photon Artificial Intelligence for Prior-Informed Assessment of Muscle Function and Pathology.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Characterization of collagen response to bone fracture healing using polarization-SHG.Scientific reports · 2022Article
- Machine learning-enabled cancer diagnostics with widefield polarimetric second-harmonic generation microscopy.Scientific reports · 2022Article
- Phasor approach of Mueller matrix optical scanning microscopy for biological tissue imaging.Biophysical journal · 2021Article
- Passive stiffness of fibrotic skeletal muscle in mdx mice relates to collagen architecture.The Journal of physiology · 2021Article
- Linear diattenuation imaging of biological tissues with near infrared Mueller scanning microscopy.Biomedical optics express · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Polarization-resolved second harmonic generation (P-SHG) microscopy is able to probe the sub-micrometer structural organization of myosin filaments within skeletal muscle. In this study, P-SHG microscopy was used to analyze the structural consequences of sepsis, which is the main cause of the critical illness polyneuromyopathy (CIPNM). Experiments conducted on two populations of rats demonstrated a significant difference of the anisotropy parameter between healthy and septic groups, indicating that P-SHG microscopy is promising for the diagnosis of CIPNM. The difference, which can be attributed to a change of myosin conformation at the sub-sarcomere scale, cannot be evidenced by classical SHG imaging.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.