ArticleBiomedical optics express2018
Attenuation correction assisted automatic segmentation for assessing choroidal thickness and vasculature with swept-source OCT.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
50 citing papers in PubMed, 76 citations in OpenAlex.
- Long-Term Effects of Intravitreal Ranibizumab Compared With Panretinal Photocoagulation on Optical Coherence Tomography Measured Choroidal Thickness and Vascularity.Translational vision science & technology · 2024Trial
- Choroidal changes correlate with type 1 neovascular activity in neovascular age-related macular degeneration and polypoidal choroidal vasculopathy.The British journal of ophthalmology · 2026Observational
- Intravitreal Gene Therapy with LX102-C01 in Neovascular Age-Related Macular Degeneration: A Phase I Dose-Escalation Study of 12-Month Safety and Efficacy Outcomes.Ophthalmology science · 2026Article
- OCT Angiography of Chorioretinal Microvasculature in Children with Type 1 and Type 2 Diabetes without Retinopathy.Ophthalmology science · 2026Article
- Correlation between renal function and OCTA parameters of the retina and choroid in early-stage diabetic patients.Journal of translational medicine · 2025Article
- Correlation of retino-choroidal thickness and vascular metrics with drusen volume as a severity marker of age-related macular degeneration.Eye (London, England) · 2025Article
- Choroidal thinning can be assessed through facial video analysis.Quantitative imaging in medicine and surgery · 2025Article
- Longitudinal SS-OCT choroidal imaging following thrombosis of the superior ophthalmic vein.American journal of ophthalmology case reports · 2024Article
- Automatic segmentation of layers in chorio-retinal complex using Graph-based method for ultra-speed 1.7 MHz wide field swept source FDML optical coherence tomography.Medical & biological engineering & computing · 2024Article
- The Impact of Carotid Endarterectomy on Choriocapillaris Perfusion.Investigative ophthalmology & visual science · 2023Observational
- Choroidal Vessel and Stromal Volumetric Analysis After Photodynamic Therapy or Focal Laser for Central Serous Chorioretinopathy.Translational vision science & technology · 2023Article
- Choroidal Changes After Anti-VEGF Therapy in AMD Eyes With Different Types of Macular Neovascularization Using Swept-Source OCT Angiography.Investigative ophthalmology & visual science · 2023Article
- Unleashing the power of optical attenuation coefficients to facilitate segmentation strategies in OCT imaging of age-related macular degeneration: perspective.Biomedical optics express · 2023Article
- Depth-dependent attenuation and backscattering characterization of optical coherence tomography by stationary iterative method.Journal of biomedical optics · 2023Article
- Viewing life without labels under optical microscopes.Communications biology · 2023Review
- Decreased Macular Choriocapillaris Perfusion in Eyes With Macular Reticular Pseudodrusen Imaged With Swept-Source OCT Angiography.Investigative ophthalmology & visual science · 2023Article
- Automated segmentation and quantification of calcified drusen in 3D swept source OCT imaging.Biomedical optics express · 2023Article
- Using beam-offset optical coherence tomography to reconstruct backscattered photon profiles in scattering media.Biomedical optics express · 2022Article
- Impact of Reticular Pseudodrusen on Choriocapillaris Flow Deficits and Choroidal Structure on Optical Coherence Tomography Angiography.Investigative ophthalmology & visual science · 2022Article
- Depth-resolved visualization and automated quantification of hyperreflective foci on OCT scans using optical attenuation coefficients.Biomedical optics express · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Swept source optical coherence tomography (SS-OCT) is being used more widely in clinical studies to investigate the choroid due to its deeper penetration under the retinal pigment epithelium and improved image quality compared with spectral domain OCT. However, automatic methods to reliably assess choroidal thickness and vasculature are still limited. This paper reports an approach that applies attenuation correction on SS-OCT structural scans to facilitate accurate automatic segmentation of the choroid and provides visualization of the choroidal vasculature without the necessity of OCT angiography. After attenuation correction, enhanced interlayer contrast at the choroidal-scleral interface was observed (from 0.13 ± 0.05 to 0.29 ± 0.10; P < 0.001). An algorithm that segmented the choroid from attenuation compensated B-scans achieved significantly higher accuracy when compared with an automated segmentation performed on regular OCT scans (91.8 ± 3.7% vs.74.5 ± 8.0%; P < 0.01). After attenuation correction,
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.