Evidence map›Paper›PMID 31065407›Full record

ArticleBiomedical optics express2018

Within-subject assessment of foveal avascular zone enlargement in different stages of diabetic retinopathy using

Giselle Lynch, Jorge S Andrade Romo, Rachel Linderman, Brian D Krawitz, Shelley Mo, Amir Zakik, Joseph Carroll, Richard B Rosen, Toco Y P Chui

Abstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
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  5. Article
  6. Article
  7. Nonperfused Retinal Capillaries-A New Method Developed on OCT and OCTA.Investigative ophthalmology & visual science · 2025
    Article
  8. Preferential Sites of Retinal Capillary Occlusion in Sickle Cell Disease.Investigative ophthalmology & visual science · 2025
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Optical coherence tomography angiography in diabetic retinopathy.Progress in retinal and eye research · 2023
    Review
  14. Article
  15. Assessing the Sensitivity of OCT-A Retinal Vasculature Metrics.Translational vision science & technology · 2023
    Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Giselle LynchOphthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 East 14th St., Suite 500, S. Bldg., New York, NY, 10003, USA.
Jorge S Andrade RomoOphthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 East 14th St., Suite 500, S. Bldg., New York, NY, 10003, USA.
Rachel LindermanCell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, WI, 53226, USA.
Brian D KrawitzOphthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 East 14th St., Suite 500, S. Bldg., New York, NY, 10003, USA.
Shelley MoOphthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 East 14th St., Suite 500, S. Bldg., New York, NY, 10003, USA.
Amir ZakikOphthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 East 14th St., Suite 500, S. Bldg., New York, NY, 10003, USA.
Joseph CarrollCell Biology, Neurobiology & Anatomy, Medical College of Wisconsin, 8701 Watertown Plank Rd., Milwaukee, WI, 53226, USA.
Richard B RosenOphthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 East 14th St., Suite 500, S. Bldg., New York, NY, 10003, USA.
Toco Y P ChuiOphthalmology, New York Eye and Ear Infirmary of Mount Sinai, 310 East 14th St., Suite 500, S. Bldg., New York, NY, 10003, USA.

Funding

MORPHOLOGY MODULEP30EY001931 · NEI · MEDICAL COLLEGE OF WISCONSIN · PI LINK, BRIAN A · 1985 to 2016
$9.8M
Characterization of vascular responses to intravitreal anti-VEGF injections in diabetic retinopathyR01EY027301 · NEI · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Yuen Ping Toco Chui · 2017 to 2026
$4.0M
Retinal Versus Cortical Contributions to Vision Loss in AlbinismR01EY024969 · NEI · MEDICAL COLLEGE OF WISCONSIN · PI CARROLL, JOSEPH, DEYOE, EDGAR A · 2015 to 2018
$2.0M
NEI NIH HHS P30 EY001931NEI NIH HHS R01 EY024969NEI NIH HHS R01 EY027301
6 · The paper itself

Abstract

Enlargement of the foveal avascular zone (FAZ) due to progressive capillary nonperfusion is associated with visual deterioration in patients with diabetic retinopathy. The FAZ area has long been considered an important clinical marker of advancing retinopathy. However, a large body of literature shows that the FAZ area varies considerably in healthy eyes, resulting in substantial overlap between controls and diabetics, thus reducing its discriminatory value. In this study, within-subject FAZ area enlargement was obtained by the comparison of the structural FAZ area to the functional FAZ area using simultaneously-acquired, corresponding

Identifiers

PMID31065407
PMCPMC6491024

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.