Evidence map›Paper›PMID 31065366›Full record

Observational studyUnited European gastroenterology journal2019

Delta neutrophil index as an early predictive marker of severe acute pancreatitis in the emergency department.

Tae Y Kim, Sun J Kim, Yoon S Kim, Jong W Lee, Eung J Park, Seok J Lee, Kyong J Lee, Yong S Cha

Registry-linked trialAbstract readObservational Study
In one paragraph

Observational study in United European gastroenterology journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04425512 (Delta Neutrophil Index and Neutrophil Lymphocyte Ratio in Differentiation of Thyroid Malignancy and Nodular Goiter), which is not on this map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04425512 nacompletednot on this map

Delta Neutrophil Index and Neutrophil Lymphocyte Ratio in Differentiation of Thyroid Malignancy and Nodular Goiter

TypeinterventionalSponsorKahramanmaras Sutcu Imam UniversityRan2014 to 2019Enrolled333ConditionsThyroid Cancer, Thyroid Nodule, Thyroid Diseases, Delta Neutrophyl IndexArmsComplete Blood Count
3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tae Y KimDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
Sun J KimDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
Yoon S KimDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0001-5929-4291
Jong W LeeDepartment of Laboratory Medicine, Konyang University Hospital, Daejeon, Republic of Korea.
Eung J ParkCenter of Biomedical Data Science, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0003-0498-5751
Seok J LeeDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.
Kyong J LeeDepartment of Internal Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0002-9175-9164
Yong S ChaDepartment of Emergency Medicine, Yonsei University Wonju College of Medicine, Wonju, Republic of Korea.ORCID 0000-0001-9897-4273

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Predicting severe acute pancreatitis (AP) in the early clinical stage is important for low morbidity and mortality. Delta neutrophil index (DNI) is used to detect infection and inflammation, but no previous studies have evaluated the usefulness of DNI as an early predictor of progression to severe AP (SAP). Methods: The medical records of patients who were diagnosed with AP at the emergency department (ED) of Wonju Severance Christian Hospital from January 2012 to August 2016 were retrospectively reviewed. The initial DNI obtained in the ED was compared with other inflammatory markers to predict SAP. Multivariate logistic regression was used for statistical analysis. Results: Of the 209 cases included in the analysis, 13 were classified as SAP. Compared to the DNI of the mild to moderately SAP group, that in the SAP group was considerably higher. The DNI showed a positive correlation with the Atlanta classification and bedside index of severity in AP. Using multivariate logistic regression analysis, DNI was an independent predictor of early SAP detection (odds ratio 1.122, 95% CI 1.045-1.205, Conclusions: The DNI measured in the ED at presentation is a potentially useful adjunctive marker to predict SAP.

Indexed as

NeutrophilsAgedFeasibility StudiesFemaleHumansLeukocyte CountMaleMiddle AgedPancreatitisPredictive Value of TestsRetrospective StudiesSeverity of Illness Indexdelta neutrophil indexPancreatitisprognosisseverity

Identifiers

PMID31065366
PMCPMC6488799

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.