Evidence map›Paper›PMID 31065310›Full record

ArticleBiomicrofluidics2019

Microfluidics on the fly: Inexpensive rapid fabrication of thermally laminated microfluidic devices for live imaging and multimodal perturbations of multicellular systems.

Megan Levis, Nilay Kumar, Emily Apakian, Cesar Moreno, Ulises Hernandez, Ana Olivares, Fernando Ontiveros, Jeremiah J Zartman

Open access · bronzeAbstract read
In one paragraph

Article in Biomicrofluidics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 21 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Shape-Programmable Three-Dimensional Microfluidic Structures.ACS applied materials & interfaces · 2022
    Article
  6. Review
  7. Microfluidics for the study of mechanotransduction.Journal of physics D: Applied physics · 2020
    Article
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Megan LevisDepartment of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Nilay KumarDepartment of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Emily ApakianDepartment of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Cesar MorenoDepartment of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Ulises HernandezDepartment of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA.ORCID 0000-0003-4114-2243
Ana OlivaresDepartment of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA.
Fernando OntiverosBiology Department, St. John Fisher College, Rochester, New York 14618, USA.
Jeremiah J ZartmanDepartment of Chemical and Biomolecular Engineering, University of Notre Dame, Notre Dame, Indiana 46556, USA.ORCID 0000-0001-7195-7203
University of Notre Dame · USSt. John Fisher College · US

Funding

Regulation and function of multicellular calcium signaling in epithelial growth and regenerationR35GM124935 · NIGMS · UNIVERSITY OF NOTRE DAME · PI ZARTMAN, JEREMIAH JAMES · 2017 to 2021
$1.9M
NIGMS NIH HHS R35 GM124935
6 · The paper itself

Abstract

Microfluidic devices provide a platform for analyzing both natural and synthetic multicellular systems. Currently, substantial capital investment and expertise are required for creating microfluidic devices using standard soft-lithography. These requirements present barriers to entry for many nontraditional users of microfluidics, including developmental biology laboratories. Therefore, fabrication methodologies that enable rapid device iteration and work "out-of-the-box" can accelerate the integration of microfluidics with developmental biology. Here, we have created and characterized low-cost hybrid polyethylene terephthalate laminate (PETL) microfluidic devices that are suitable for cell and micro-organ culture assays. These devices were validated with mammalian cell lines and the

Identifiers

PMID31065310
PMCPMC6486393
OpenAlexW2941421140

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.