ArticleBiomicrofluidics2019
Simple and low-cost production of hybrid 3D-printed microfluidic devices.
Article in Biomicrofluidics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
22 citing papers in PubMed, 57 citations in OpenAlex.
- Synergistic Advances in Additive Manufacturing and Surface Engineering for Polymeric Biomedical Devices.ACS polymers Au · 2025Review
- Augmented 3D Printing for Multiscale Microphysiological Systems.Small (Weinheim an der Bergstrasse, Germany) · 2025Review
- Mechanistic Modelling of Coupled UV Energy Penetration and Resin Flow Dynamics in Digital Light Processing (DLP)-Based Microfluidic Chip Printing.Micromachines · 2025Article
- Transformation gap from research findings to large-scale commercialized products in microfluidic field.Materials today. Bio · 2024Review
- A Thorough Review of Emerging Technologies in Micro- and Nanochannel Fabrication: Limitations, Applications, and Comparison.Micromachines · 2024Review
- Advancing 3D printed microfluidics with computational methods for sweat analysis.Mikrochimica acta · 2024Review
- Processes for the 3D Printing of Hydrodynamic Flow-Focusing Devices.Micromachines · 2023Article
- Design and High-Resolution Analysis of an Efficient Periodic Split-and-Recombination Microfluidic Mixer.Micromachines · 2022Article
- The Fabrication and Bonding of Thermoplastic Microfluidics: A Review.Materials (Basel, Switzerland) · 2022Review
- Bonding Strategies for Thermoplastics Applicable for Bioanalysis and Diagnostics.Micromachines · 2022Review
- A Review of Microfluidic Experimental Designs for Nanoparticle Synthesis.International journal of molecular sciences · 2022Review
- A novel hardmask-to-substrate pattern transfer method for creating 3D, multi-level, hierarchical, high aspect-ratio structures for applications in microfluidics and cooling technologies.Scientific reports · 2022Article
- Recent Advances in Thermoplastic Microfluidic Bonding.Micromachines · 2022Review
- Multiplexed and simultaneous biosensing in a 3D-printed portable six-well smartphone operated electrochemiluminescence standalone point-of-care platform.Mikrochimica acta · 2022Article
- Time-efficient fabrication method for 3D-printed microfluidic devices.Scientific reports · 2022Article
- Lab-on-a-chip technologies for food safety, processing, and packaging applications: a review.Environmental chemistry letters · 2022Review
- The Development of Biomimetic Aligned Skeletal Muscles in a Fully 3D Printed Microfluidic Device.Biomimetics (Basel, Switzerland) · 2021Article
- Can 3D Printing Bring Droplet Microfluidics to Every Lab?-A Systematic Review.Micromachines · 2021Review
- Consistent ultra-long DNA sequencing with automated slow pipetting.BMC genomics · 2021Article
- Low-cost and open-source strategies for chemical separations.Journal of chromatography. A · 2021Review
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The use of three-dimensional (3D) printing for the fabrication of microfluidic chips has attracted considerable attention among researchers. This low-cost fabrication method allows for rapid prototyping and the creation of complex structures; however, these devices lack optical transparency, which greatly hinders the characterization and quantification of experiment results. To address this problem, integrating a transparent substrate with a 3D-printed chip is an effective approach. In this study, we present a solvent bonding method of poly(methyl methacrylate) (PMMA) and acrylonitrile butadiene styrene (ABS) thermoplastic materials for the creation of optically detectable 3D-printed microfluidic devices. To achieve an excellent bonding between PMMA and ABS substrates, we used spray coating as a method for the distribution of ethanol solution followed by UV exposure and post-annealing step to improve the bonding strength. We fabricated a microfluidic chip with S-microchannel to characterize the bonding protocol, and other two application-oriented microfluidic chips, including a 3D split-and-recombine-based passive micromixer, and an integrated microchip for the mixing of two streams of liquid prior to the formation of double-emulsion droplets, to evaluate the efficacy of the proposed scheme. As a result, at least eight bars of the bonding strength between PMMA/ABS substrates was achieved, and the ability of producing optically detectable 3D-printed microfluidic devices based on this bonding method was confirmed.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.