Evidence map›Paper›PMID 31065301›Full record

ArticleThe Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale2019

Role of Probiotics in

Maria Pina Dore, Stefano Bibbò, Giovanni Mario Pes, Ruggero Francavilla, David Y Graham

Open access · goldAbstract read
In one paragraph

Article in The Canadian journal of infectious diseases & medical microbiology = Journal canadien des maladies infectieuses et de la microbiologie medicale, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 1 pooled it
6.6field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 1 synthesis or guideline pooled it, 42 citations in OpenAlex.

  1. Efficacy of probiotics pretreatment inAnnals of medicine · 2025
    Pooled it
  2. Trial
  3. Study of the effect of LactobacillusFrontiers in immunology · 2023
    Trial
  4. Trial
  5. Trial
  6. Trial
  7. Beyond Antibiotics: Alternative Strategies TargetingExpert reviews in molecular medicine · 2026
    Review
  8. Review
  9. Article
  10. Review
  11. Review
  12. The Aging Stomach: Clinical Implications ofInternational journal of molecular sciences · 2024
    Review
  13. Article
  14. Probiotics and autoprobiotics for treatment ofWorld journal of clinical cases · 2023
    Review
  15. Review
  16. Review
  17. Review
  18. Current and future perspectives forFrontiers in cellular and infection microbiology · 2022
    Review
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Maria Pina DoreDipartimento di Medicina Clinica e Sperimentale, University of Sassari, Sassari, Italy.ORCID 0000-0001-7305-3531
Stefano BibbòDipartimento di Medicina Clinica e Sperimentale, University of Sassari, Sassari, Italy.ORCID 0000-0002-8043-4807
Giovanni Mario PesDipartimento di Medicina Clinica e Sperimentale, University of Sassari, Sassari, Italy.ORCID 0000-0003-3265-2823
Ruggero FrancavillaDepartment of Interdisciplinary Medicine, University Hospital of Bari, Bari, Italy.
David Y GrahamDepartment of Medicine, Michael E. DeBakey VA Medical Center and Baylor College of Medicine, Houston, TX, USA.ORCID 0000-0002-6908-8317
University of Sassari · ITMichael E. DeBakey VA Medical Center · USUniversity of Bari Aldo Moro · IT

Funding

Tissue Analysis & Molecular Imaging CoreP30DK056338 · NIDDK · BAYLOR COLLEGE OF MEDICINE · PI James Versalovic · 2001 to 2026
$28.3M
NIDDK NIH HHS P30 DK056338
6 · The paper itself

Abstract

backgroundMeta-analyses involving >4000 subjects with probiotics added to antimicrobial

aimTo evaluate whether administration of

methodsThis was a double-blind placebo-controlled randomized 2-site study of

resultsRecruitment was halted after 56 subjects because of the low cure rate; there were 8 dropouts; 48 subjects completed therapy (71% women, average age 49 years). The cure rates per protocol were 3/24 (12.5%; 95% CI 2.6-32%) with

conclusion

Identifiers

PMID31065301
PMCPMC6466906
OpenAlexW2927286302

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.