ArticleThe ISME journal2019
A novel outer membrane β-1,6-glucanase is deployed in the predation of fungi by myxobacteria.
Article in The ISME journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 52 papers.
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Who cites it
52 citing papers in PubMed, 81 citations in OpenAlex.
- Article
- Enhanced Endophytic Colonization of Flavobacterium Promotes Plant Resistance to Fusarium Wilt.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Predatory Mechanisms of Myxobacteria and Their Potential in the Development of Biocontrol Agents.Journal of microbiology and biotechnology · 2026Review
- The Structure, Biosynthesis, and Function of β-1,6-Glucan in the Fungal Cell Wall.Biomolecules · 2026Review
- Identification of Novel Polysaccharide from Myxococcus xanthus and its Function in Developmental Sporulation.Current microbiology · 2026Article
- Protease-Mediated Dual Action Against Rice Blast: Suppression of Magnaporthe oryzae Ergosterol Biosynthesis Pathway and Enhancement of Rice Disease Resistance by Bacillus amyloliquefaciens SN16-1.Plant, cell & environment · 2026Article
- A predator-prey interaction between myxobacteria and fungi mediated by outer membrane vesicles.Journal of advanced research · 2026Article
- Role of DKxanthenes inJournal of microbiology and biotechnology · 2026Article
- Article
- Precision hydrolysis: tailored yeast processing enzymes for yeast-based products.Applied microbiology and biotechnology · 2026Review
- PredatoryFrontiers in microbiology · 2026Article
- Biocontrol of watermelon Fusarium wilt caused byFrontiers in microbiology · 2026Article
- Myxococcus fulvus, as a Potential Isolate to be used as a Future Biocontrol Agent.Current microbiology · 2025Article
- The β-1,6-glucanase MoGlu16 is Required for Mycelia Growth and Pathogenicity of Magnaporthe oryzae.Current microbiology · 2025Article
- Myxobacteria: Versatile cell factories of novel commercial enzymes for bio-manufacturing.Biotechnology advances · 2025Review
- Foliar Application of Chlorella Supernatant Protects Turfgrass against Clarireedia jacksonii by Eliciting Induced Resistance and Modulating the Rhizosphere Microbiota.The plant pathology journal · 2025Article
- Article
- Antifungal characterizations of a novel endo-β-1,6-glucanase from Flavobacterium sp. NAU1659.Applied microbiology and biotechnology · 2024Article
- A novel xylanase from a myxobacterium triggers a plant immune response in Nicotiana benthamiana.Molecular plant pathology · 2024Article
- AApplied and environmental microbiology · 2024Article
Corrections and comments
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Authors and funding
16 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Myxobacterial predation on bacteria has been investigated for several decades. However, their predation on fungi has received less attention. Here, we show that a novel outer membrane β-1,6-glucanase GluM from Corallococcus sp. strain EGB is essential for initial sensing and efficient decomposition of fungi during predation. GluM belongs to an unstudied family of outer membrane β-barrel proteins with potent specific activity up to 24,000 U/mg, whose homologs extensively exist in myxobacteria. GluM was able to digest fungal cell walls efficiently and restrict Magnaporthe oryzae infection of rice plants. Genetic complementation with gluM restored the fungal predation ability of Myxococcus xanthus CL1001, which was abolished by the disruption of gluM homolog oar. The inability to prey on fungi with cell walls that lack β-1,6-glucans indicates that β-1,6-glucans are targeted by GluM. Our results demonstrate that GluM confers myxobacteria with the ability to feed on fungi, and provide new insights for understanding predator-prey interactions. Considering the attack mode of GluM, we suggest that β-1,6-glucan is a promising target for the development of novel broad-spectrum antifungal agents.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.