Evidence map›Paper›PMID 31064977›Full record

ArticleCell death & disease2019

The expression and function of TRPV4 channels in primate retinal ganglion cells and bipolar cells.

Fan Gao, Zhuo Yang, Roy A Jacoby, Samuel M Wu, Ji-Jie Pang

Open access · goldAbstract read
In one paragraph

Article in Cell death & disease, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 38 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Immunohistochemistry and Spatial Density of Müller Cells in the Human Fovea.Investigative ophthalmology & visual science · 2025
    Article
  5. Review
  6. Review
  7. The Variety of Mechanosensitive Ion Channels in Retinal Neurons.International journal of molecular sciences · 2024
    Review
  8. Article
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Fan GaoDepartment of Ophthalmology, Baylor College of Medicine, One Baylor Plaza, NC 205, Houston, TX, 77030, USA.
Zhuo YangDepartment of Ophthalmology, Baylor College of Medicine, One Baylor Plaza, NC 205, Houston, TX, 77030, USA.
Roy A JacobyDepartment of Ophthalmology, Baylor College of Medicine, One Baylor Plaza, NC 205, Houston, TX, 77030, USA.
Samuel M WuDepartment of Ophthalmology, Baylor College of Medicine, One Baylor Plaza, NC 205, Houston, TX, 77030, USA.
Ji-Jie PangDepartment of Ophthalmology, Baylor College of Medicine, One Baylor Plaza, NC 205, Houston, TX, 77030, USA. jpang@bcm.edu.
Baylor College of Medicine · US

Funding

VISION RESEARCH CENTERP30EY002520 · NEI · BAYLOR COLLEGE OF MEDICINE · PI Samuel M Wu · 1985 to 2026
$14.8M
PHYSIOLOGY AND PHARMACOLOGY OF SYNAPSES IN THE RETINAR01EY004446 · NEI · BAYLOR COLLEGE OF MEDICINE · PI WU, SAMUEL M · 1985 to 2014
$5.4M
ROD AND CONE SIGNALING PATHWAYS IN MAMMALIAN RETINAR01EY019908 · NEI · BAYLOR COLLEGE OF MEDICINE · PI WU, SAMUEL M · 2010 to 2020
$3.8M
NEI NIH HHS P30 EY002520NEI NIH HHS R01 EY004446NEI NIH HHS R01 EY019908
6 · The paper itself

Abstract

The transient receptor potential vanilloid 4 (TRPV4) channel may be opened by mechanical stimuli to mediate Ca

Indexed as

AnimalsLeucineMacaca mulattaPapio cynocephalusPhorbol EstersPressureRetinaRetinal Bipolar CellsRetinal Ganglion CellsSulfonamidesSynaptic PotentialsTemperatureTRPV Cation ChannelsLeucineN-(1-((4-(2-(((2,4-dichlorophenyl)sulfonyl)amino)-3-hydroxypropanoyl)-1-piperazinyl)carbonyl)-3-methylbutyl)-1-benzothiophene-2-carboxamidephorbol-12,13-didecanoatePhorbol EstersSulfonamidesTRPV Cation Channels

Identifiers

PMID31064977
PMCPMC6504919
OpenAlexW2944021118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.