Evidence map›Paper›PMID 31064860›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

Transcriptional Regulation of the Glutamate/GABA/Glutamine Cycle in Adult Glia Controls Motor Activity and Seizures in

David Mazaud, Benjamin Kottler, Catarina Gonçalves-Pimentel, Sandra Proelss, Nadine Tüchler, Celine Deneubourg, Yoshihiro Yuasa, Celine Diebold, Heinz Jungbluth, Eric C Lai and 3 more

Open access · hybridAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
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  7. A transporter's doom or destiny:Frontiers in molecular neuroscience · 2024
    Review
  8. Article
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  10. Article
  11. Review
  12. Review
  13. Comparative study of rivastigmine and galantamine on the transgenicCurrent research in pharmacology and drug discovery · 2022
    Article
  14. Resources and Methods for the Analysis of MicroRNA Function in Drosophila.Methods in molecular biology (Clifton, N.J.) · 2022
    Review
  15. Article
  16. Frontiers in neuroscience · 2022
    Article
  17. TheGenome research · 2021
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 3 countries.

David MazaudDepartment of Basic and Clinical Neuroscience, King's College London, SE5 9NU London, United Kingdom.ORCID 0000-0003-3998-9330
Benjamin KottlerDepartment of Basic and Clinical Neuroscience, King's College London, SE5 9NU London, United Kingdom.ORCID 0000-0002-4551-5791
Catarina Gonçalves-PimentelDepartment of Basic and Clinical Neuroscience, King's College London, SE5 9NU London, United Kingdom.ORCID 0000-0003-1181-3907
Sandra ProelssDepartment of Basic and Clinical Neuroscience, King's College London, SE5 9NU London, United Kingdom.
Nadine TüchlerDepartment of Basic and Clinical Neuroscience, King's College London, SE5 9NU London, United Kingdom.
Celine DeneubourgDepartment of Basic and Clinical Neuroscience, King's College London, SE5 9NU London, United Kingdom.ORCID 0000-0002-8854-6619
Yoshihiro YuasaInstitut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France.
Celine DieboldInstitut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France.
Heinz JungbluthDepartment of Basic and Clinical Neuroscience, King's College London, SE5 9NU London, United Kingdom.
Eric C LaiDepartment of Developmental Biology, Sloan-Kettering Institute, New York, New York 10065.ORCID 0000-0002-8432-5851
Frank HirthDepartment of Basic and Clinical Neuroscience, King's College London, SE5 9NU London, United Kingdom.ORCID 0000-0001-8581-9450
Angela GiangrandeInstitut de Génétique et de Biologie Moléculaire et Cellulaire, 67404 Illkirch, France.
Manolis FantoDepartment of Basic and Clinical Neuroscience, King's College London, SE5 9NU London, United Kingdom, manolis.fanto@kcl.ac.uk.ORCID 0000-0001-7807-2563
King's College London · GBCentre National de la Recherche Scientifique · FRKettering University · US

Funding

X-RAY CRYSTALLOGRAPHYP30CA008748 · NCI · SLOAN-KETTERING INSTITUTE FOR CANCER RES · PI SELWYN M VICKERS · 1985 to 2026
$347.4M
Mechanism and regulation of Hu family RNA binding proteins during neural alternative polyadenylationR01NS083833 · NINDS · SLOAN-KETTERING INST CAN RESEARCH · PI LAI, ERIC C · 2014 to 2023
$5.4M
Biotechnology and Biological Sciences Research Council BB/N001230/1Medical Research Council G0701498Medical Research Council MR/L010666/1Motor Neurone Disease Association HIRTH/OCT13/868-792Motor Neurone Disease Association HIRTH/OCT16/890-792National Centre for the Replacement, Refinement and Reduction of Animals in Research NC/L000199/1NCI NIH HHS P30 CA008748NINDS NIH HHS R01 NS083833Parkinson's UK G-0714
6 · The paper itself

Abstract

The fruitfly

Indexed as

Gene Expression RegulationMotor ActivityAnimalsDrosophila melanogasterDrosophila ProteinsFemalegamma-Aminobutyric AcidGlutamic AcidGlutamineHomeodomain ProteinsMaleMicroRNAsNeurogliaSeizuresDrosophila Proteinsgamma-Aminobutyric AcidGlutamic AcidGlutamineHomeodomain ProteinsMicroRNAsrepo protein, DrosophilaDrosophilagliaglutamate/GABA/glutaminerepo

Identifiers

PMID31064860
PMCPMC6607755
OpenAlexW2944183703

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.