Evidence map›Paper›PMID 31064859›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2019

CAMK2-Dependent Signaling in Neurons Is Essential for Survival.

Martijn J Kool, Martina Proietti Onori, Nils Z Borgesius, Jolet E van de Bree, Minetta Elgersma-Hooisma, Enzo Nio, Karel Bezstarosti, Gabriëlle H S Buitendijk, Mehrnoush Aghadavoud Jolfaei, Jeroen A A Demmers and 2 more

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed, 91 citations in OpenAlex.

  1. Enteric-colonizedGut microbes · 2026
    Article
  2. [CAMK2a Regulates Paclitaxel Resistance in Oral Squamous Cell Carcinoma Cells by Activating the ERK Signaling Pathway].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
  3. Article
  4. DifferentialProceedings of the National Academy of Sciences of the United States of America · 2026
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  15. Neuroplasticity in the transition from acute to chronic pain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2024
    Review
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  20. Role of CAMK2D in neurodevelopment and associated conditions.American journal of human genetics · 2024
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 2 institutions in 2 countries.

Martijn J KoolDepartment of Neuroscience.ORCID 0000-0002-5640-8780
Martina Proietti OnoriDepartment of Neuroscience.ORCID 0000-0003-0360-2894
Nils Z BorgesiusDepartment of Neuroscience.ORCID 0000-0002-2090-3931
Jolet E van de BreeDepartment of Neuroscience.
Minetta Elgersma-HooismaDepartment of Neuroscience.
Enzo NioDepartment of Neuroscience.
Karel BezstarostiProteomics Center, Erasmus MC, 3015 GD, Rotterdam, The Netherlands.
Gabriëlle H S BuitendijkDepartment of Neuroscience.
Mehrnoush Aghadavoud JolfaeiDepartment of Neuroscience.
Jeroen A A DemmersProteomics Center, Erasmus MC, 3015 GD, Rotterdam, The Netherlands.ORCID 0000-0002-8757-9611
Ype ElgersmaDepartment of Neuroscience, y.elgersma@erasmusmc.nl g.vanwoerden@erasmusmc.nl.ORCID 0000-0002-3758-1297
Geeske M van WoerdenDepartment of Neuroscience, y.elgersma@erasmusmc.nl g.vanwoerden@erasmusmc.nl.ORCID 0000-0003-2492-9239
NeuroDevelopment Center · USErasmus MC · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ca

Indexed as

AnimalsBrainCalcium-Calmodulin-Dependent Protein Kinase Type 2FemaleGene DeletionGerm-Line MutationLong-Term PotentiationMaleMiceMice, Inbred C57BLNeurogenesisNeuronsPost-Synaptic DensityCalcium-Calmodulin-Dependent Protein Kinase Type 2Camk2a protein, mouseCamk2b protein, mouseCAMK2hippocampussurvivalsynaptic plasticity

Identifiers

PMID31064859
PMCPMC6616294
OpenAlexW2943914132

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.