ArticleCancer research2019
Preexisting Commensal Dysbiosis Is a Host-Intrinsic Regulator of Tissue Inflammation and Tumor Cell Dissemination in Hormone Receptor-Positive Breast Cancer.
Open access · greenAbstract read
In one paragraph
Article in Cancer research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 125 papers, 3 of them syntheses that pooled it.
0numbers the graph read from it
0cells of the map it votes in
125citing papers in PubMed, 3 pooled it
9.5field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
125 citing papers in PubMed, 3 syntheses or guidelines pooled it, 195 citations in OpenAlex.
- Guideline for designing microbiome studies in neoplastic diseases.GeroScience · 2024Guideline
- Bibliometric and visual analysis of human microbiome-breast cancer interactions: current insights and future directions.Frontiers in microbiology · 2024Pooled it
- Gut OncoMicrobiome Signatures (GOMS) as next-generation biomarkers for cancer immunotherapy.Nature reviews. Clinical oncology · 2023Pooled it
- Efficacy, safety, and predictive biomarkers of neoadjuvant nab-paclitaxel and pembrolizumab in hormone receptor-positive breast cancer: A randomized pilot trial.Nature communications · 2025Trial
- Review
- Commensal Dysbiosis Alters Primary Bile Acid Signaling to Drive Mammary Gland Inflammation and Breast Tumor Dissemination.Cancer research · 2026Article
- Bifidobacterium pseudocatenulatum capsular exopolysaccharide enhances systemic anti-tumour immunity in pre-clinical breast cancer.Research square · 2026Article
- Enterococcus faecalis Extracellular Vesicles Deliver the Bacterial GTPase Obg to Hijack mTOR Signalling in Hepatocellular Carcinoma.Journal of extracellular vesicles · 2026Article
- The Role of Lactobacillus Strain Probiotics in Breast Cancer: Strain-Specific Mechanisms and Therapeutic Potential Beyond Probiotics.Probiotics and antimicrobial proteins · 2026Review
- Exploratory Pilot Multi-Omics Profiling of Gut Microbiota and Metabolic Features in Patients with Prolactinoma.Cancer management and research · 2026Article
- The Impact of Microbiome on Breast Cancer and Regulatory Strategies.Microorganisms · 2025Review
- [Gut microbiota involved in cancer invasion and metastasis].Zhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Review
- Antibiotic use and survival from breast cancer: A population-based cohort study in England and Wales.Nature communications · 2025Article
- Microbiota-directed lactic acid depleting nanoenzyme reactivates antitumor immunity and chemosensitivity in hypoxic tumor.Materials today. Bio · 2025Article
- Interaction between the breast tumor microenvironment and gut microbiome.Gut microbes · 2025Review
- MIIST305 mitigates gastrointestinal acute radiation syndrome injury and ameliorates radiation-induced gut microbiome dysbiosis.Gut microbes · 2025Article
- Integrative mendelian randomization and multi-omics analysis reveal a gut microbiota-metabolite-CXCL10 axis in breast cancer.AMB Express · 2025Article
- Exploring the Microbiome in Breast Cancer: The Role ofMicroorganisms · 2025Review
- Gastric Cancer and Microbiota: Exploring the Microbiome's Role in Carcinogenesis and Treatment Strategies.Life (Basel, Switzerland) · 2025Review
- Causal association between gut microbiota and endometrial cancer in European and East Asian populations: a two-sample Mendelian randomization study.BMC women's health · 2025Article
65 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
10 authors at 2 institutions in 1 country.
Claire Buchta RoseanDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia.
Raegan R BosticDepartment of Cell Biology, University of Virginia, Charlottesville, Virginia.ORCID https://orcid.org/0000-0003-1892-5418
Joshua C M FereyUniversity of Virginia School of Medicine, Charlottesville, Virginia.
Tzu-Yu FengDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia.ORCID https://orcid.org/0000-0001-8650-3781
Francesca N AzarDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia.
Kenneth S TungDepartment of Pathology, University of Virginia, Charlottesville, Virginia.
Mikhail G DozmorovDepartment of Biostatistics, Virginia Commonwealth University, Richmond, Virginia.ORCID https://orcid.org/0000-0002-0086-8358
Ekaterina SmirnovaDepartment of Biostatistics, Virginia Commonwealth University, Richmond, Virginia.
Paula D BosDepartment of Pathology, Massey Cancer Center, Virginia Commonwealth University, Richmond, Virginia.ORCID https://orcid.org/0000-0001-8035-5888
Melanie R RutkowskiDepartment of Microbiology, Immunology, and Cancer Biology, University of Virginia, Charlottesville, Virginia. mr2ee@virginia.edu.
University of Virginia · USVirginia Commonwealth University · US
Funding
Women's Oncology Program - WONP30CA044579 · NCI · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Jay William FOX · 1987 to 2026
$72.1MINTERDISCIPLINARY TRAINING PROGRAM IN IMMUNOLOGYT32AI007496 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI Michael G. Brown, Coleen A McNamara · 1995 to 2026
$10.2MTraining in Cell and Molecular BiologyT32GM139787 · NIGMS · UNIVERSITY OF VIRGINIA · PI Bryce Paschal · 2021 to 2026
$2.5MGut microbiome-mediated differences within the pre-malignant mammary tissue environment enhance early breast tumor metastasisR01CA262634 · NCI · UNIVERSITY OF VIRGINIA · PI Melanie R Rutkowski · 2023 to 2026
$1.8MBiodefense Short-Term Training for Minority StudentT35AI060528 · NIAID · UNIVERSITY OF VIRGINIA CHARLOTTESVILLE · PI HALME, ADRIAN J, PETRI, WILLIAM A · 2004 to 2024
$1.3MNCI NIH HHS P30 CA044579NCI NIH HHS R01 CA262634NIAID NIH HHS T32 AI007496NIAID NIH HHS T35 AI060528NIGMS NIH HHS T32 GM139787
Abstract
It is unknown why some patients with hormone receptor-positive (HR
Indexed as
Breast NeoplasmsGastrointestinal MicrobiomeDysbiosisHumansInflammationSymbiosisTumor Microenvironment
Identifiers
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.