Evidence map›Paper›PMID 31064836›Full record

ArticlemBio2019

Massively Parallel Fitness Profiling Reveals Multiple Novel Enzymes in

Mitchell G Thompson, Jacquelyn M Blake-Hedges, Pablo Cruz-Morales, Jesus F Barajas, Samuel C Curran, Christopher B Eiben, Nicholas C Harris, Veronica T Benites, Jennifer W Gin, William A Sharpless and 10 more

Open access · goldAbstract read
In one paragraph

Article in mBio, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.9field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 78 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. A Genetically Encoded Biosensor for Characterizing Transport and Metabolism of Glutarate.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. EngineeringMetabolic engineering communications · 2025
    Article
  11. Article
  12. Replacing rice straw with peanut vine andAnimal nutrition (Zhongguo xu mu shou yi xue hui) · 2025
    Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Tuning a high performing multiplexed-CRISPRiMetabolic engineering communications · 2022
    Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors at 4 institutions in 3 countries.

Mitchell G ThompsonJoint BioEnergy Institute, Emeryville, California, USA.
Jacquelyn M Blake-HedgesJoint BioEnergy Institute, Emeryville, California, USA.
Pablo Cruz-MoralesJoint BioEnergy Institute, Emeryville, California, USA.
Jesus F BarajasBiological Systems & Engineering Division, Lawrence Berkeley National Laboratory, Berkeley, California, USA.
Samuel C CurranJoint BioEnergy Institute, Emeryville, California, USA.
Christopher B EibenJoint BioEnergy Institute, Emeryville, California, USA.
Nicholas C HarrisDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, California, USA.
Veronica T BenitesJoint BioEnergy Institute, Emeryville, California, USA.
Jennifer W GinJoint BioEnergy Institute, Emeryville, California, USA.
William A SharplessJoint BioEnergy Institute, Emeryville, California, USA.
Frederick F TwiggDepartment of Chemical and Biomolecular Engineering, University of California, Berkeley, Berkeley, California, USA.
Will SkyrudDepartment of Chemistry, University of California, Berkeley, Berkeley, California, USA.
Rohith N KrishnaJoint BioEnergy Institute, Emeryville, California, USA.
Jose Henrique PereiraJoint BioEnergy Institute, Emeryville, California, USA.
Edward E K BaidooJoint BioEnergy Institute, Emeryville, California, USA.
Christopher J PetzoldJoint BioEnergy Institute, Emeryville, California, USA.
Paul D AdamsJoint BioEnergy Institute, Emeryville, California, USA.
Adam P ArkinJoint Program in Bioengineering, University of California, Berkeley, Berkeley, California, USA.
Adam M DeutschbauerDepartment of Plant and Microbial Biology, University of California, Berkeley, Berkeley, California, USA.
Jay D KeaslingJoint BioEnergy Institute, Emeryville, California, USA jdkeasling@lbl.gov.
Joint BioEnergy Institute · USUniversity of California, Berkeley · USLawrence Berkeley National Laboratory · USTecnológico de Monterrey · MX

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Despite intensive study for 50 years, the biochemical and genetic links between lysine metabolism and central metabolism in

Indexed as

Genetic FitnessLysineMetabolic Networks and PathwaysPseudomonas putidaLysinebiochemistrybiotechnologygenomicsmetabolismtransposons

Identifiers

PMID31064836
PMCPMC6509195
OpenAlexW2897783063

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.