Evidence map›Paper›PMID 31064767›Full record

ArticleLife science alliance2019

Development of a new monoclonal antibody specific to mouse Vγ6 chain.

Shinya Hatano, Xin Tun, Naoto Noguchi, Dan Yue, Hisakata Yamada, Xun Sun, Mitsuru Matsumoto, Yasunobu Yoshikai

Open access · goldAbstract read
In one paragraph

Article in Life science alliance, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
  3. Restriction of innate Tγδ17 cell plasticity by an AP-1 regulatory axis.bioRxiv : the preprint server for biology · 2024
    Article
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  13. Article
  14. Innate Lymphocytes in Psoriasis.Frontiers in immunology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Shinya HatanoDivision of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan hatano@bioreg.kyushu-u.ac.jp.ORCID 0000-0002-4933-8171
Xin TunDivision of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Naoto NoguchiDivision of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Dan YueDivision of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Hisakata YamadaDivision of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Xun SunDepartment of Immunology, China Medical University, Shenyang, China.
Mitsuru MatsumotoDivision of Molecular Immunology, Institute for Enzyme Research, Tokushima University, Tokushima, Japan.
Yasunobu YoshikaiDivision of Host Defense, Medical Institute of Bioregulation, Kyushu University, Fukuoka, Japan.
Kyushu University · JPChina Medical University · CNTokushima University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

There are seven Vγ gene segments in the TCR γ chain loci of mice. We developed monoclonal antibodies (mAbs) specific to the Vγ6 chain (Heilig & Tonegawa nomenclature). By immunizing Vγ4/6 KO mice with complementarity-determining region peptides in Vγ6 chains, we generated three hybridomas. These hybridomas produced mAbs capable of cell surface staining of Vγ6/Vδ1 gene-transfected T-cell line lacking TCR as well as of Vγ1

Indexed as

Antibody SpecificityAnimalsAntibodies, MonoclonalAntibody FormationCell Line, TumorFemaleImmunizationImmunophenotypingMiceReceptors, Antigen, T-Cell, gamma-deltaT-LymphocytesAntibodies, MonoclonalReceptors, Antigen, T-Cell, gamma-delta

Identifiers

PMID31064767
PMCPMC6504751
OpenAlexW2944245734

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.