ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2019
Comorbidity in patients with cardiovascular disease in primary care: a cohort study with routine healthcare data.
Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
60 citing papers in PubMed, 131 citations in OpenAlex.
- Optimizing Non-invasive Fractional Flow Reserve Estimation with Machine Learning-Enhanced 1D Hemodynamic Modeling.Cardiovascular engineering and technology · 2026Article
- Comorbidity patterns and inpatient expenditure among patients with coronary heart disease in China.BMC public health · 2026Article
- Vital Exhaustion in Hospitalized Patients with Cardiovascular Disease: Associations with Anxiety and Insomnia-A Cross-Sectional Study.Journal of cardiovascular development and disease · 2026Article
- Impact of Heart Disease and Multimorbidity on Oral Frailty in Japanese Community-Dwelling Older Adults.Circulation reports · 2026Article
- Assessment of Serbian adults' diet through cluster analysis approach - findings from the national health interview survey.BMC public health · 2026Article
- National Mortality Trends, Disparities, and Forecasted Burden of Atrial Fibrillation and Heart Failure with Underlying Ischemic Heart Disease Among Older Adults in the United States, 1999-2023.Journal of epidemiology and global health · 2026Article
- Educational Attainment and Risk of Coronary Heart Disease Across Age Groups: Analysis of the 2021 BRFSS National Survey.Healthcare (Basel, Switzerland) · 2026Article
- Evaluating the modified spinal cord injury secondary conditions scale (SCI-SCS) combining severity and mortality-based weights.Spinal cord · 2026Article
- Sotagliflozin Enhances Left Ventricular Function and Myocardial Perfusion in Chronic Myocardial Ischemia Through Metabolic and Redox Remodeling.Arteriosclerosis, thrombosis, and vascular biology · 2026Article
- An Australian experience of the Rapid Access Chest Pain Assessment Clinic.Scientific reports · 2025Observational
- Program theory and economic insights of a comprehensive geriatric assessment for frail heart failure patients.BMC geriatrics · 2025Article
- Genetic crossroads of cardiovascular disease and its comorbidities: toward holistic therapeutic strategies.BMC medical genomics · 2025Article
- Impact of oral health conditions on the quality of life of hospitalized cardiovascular patients: evidence from Brazil.BMC cardiovascular disorders · 2025Article
- State-of-the-art wearable sensors for cardiovascular health: a review.NPJ cardiovascular health · 2025Review
- Spatial heterogeneity and its influencing factors of cardiometabolic multimorbidity in a natural community population: a study based on Lingwu city, rural Northwest China.BMC public health · 2025Article
- Age, morbidity, and time to death: End-of-life expenditures on health care for the young-old population.The European journal of health economics : HEPAC : health economics in prevention and care · 2025Article
- Development and validation of a nomogram for predicting endoscopic healing in crohn's disease patients receiving infliximab treatment.BMC gastroenterology · 2025Article
- Mitigating Bias in Opportunistic Screening for MACE with Causal Reasoning.IEEE transactions on artificial intelligence · 2025Article
- Co-Occurring Diseases and Mortality in Patients With Chronic Heart Disease, Modeling Their Dynamically Expanding Disease Portfolios: Nationwide Register Study.JMIR cardio · 2025Article
- Semaglutide Improves Myocardial Perfusion and Performance in a Large Animal Model of Coronary Artery Disease.Arteriosclerosis, thrombosis, and vascular biology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundComorbidity is a major public health issue, which challenges health care configured around single diseases.
aimTo provide an overview of frequent disease combinations of one and two additional chronic diseases and groups among patients with cardiovascular disease (CVD) in general practice. DESIGN AND
settingMedical record data from the Julius General Practitioners' Network of 226 670 patients registered in 2015-2016 in Utrecht, the Netherlands, were collected and examined.
methodPrevalences and combinations of one and two comorbid conditions were determined, by age and sex, in four populations of patients with CVD: heart failure, peripheral arterial disease (PAD), coronary heart disease (CHD), or stroke. Using logistic regression analyses, the authors examined whether comorbid conditions were significantly more prevalent in patients with a specific cardiovascular condition compared with those without.
resultsLow vision, diabetes mellitus, back/neck problems, osteoarthritis, chronic obstructive pulmonary disease (COPD), and cancer were the most prevalent non-cardiovascular conditions and ranked in the top five of non-cardiovascular comorbid conditions in the different CVDs studied, irrespective of patient age and sex. Of these, diabetes, COPD, and low vision were statistically significantly more prevalent in all four cardiovascular conditions when compared with patients without the respective disease. Over the life span, the majority of the comorbid conditions were most prevalent in patients with heart failure, directly followed by those with PAD; they were less prevalent in patients with CHD and stroke.
conclusionComorbid conditions are very common in patients with CVD, even in younger age groups. To ensure efficient and effective treatment, organisational adaptations may be required in the healthcare system to accommodate comorbid conditions in patients with CVD.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.