Evidence map›Paper›PMID 31064642›Full record

ArticleDeutsches Arzteblatt international2019

The Diagnosis and Treatment of Pinworm Infection.

Sebastian Wendt, Henning Trawinski, Stefan Schubert, Arne C Rodloff, Joachim Mössner, Christoph Lübbert

Open access · greenAbstract read
In one paragraph

Article in Deutsches Arzteblatt international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 56 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
56citing papers in PubMed, 2 pooled it
8.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

56 citing papers in PubMed, 2 syntheses or guidelines pooled it, 106 citations in OpenAlex.

  1. Prevalence and Epidemiological Patterns ofMedical sciences (Basel, Switzerland) · 2025
    Pooled it
  2. Pooled it
  3. Trial
  4. Article
  5. Article
  6. Article
  7. Article
  8. [A classical diagnosis with unexpected background].Chirurgie (Heidelberg, Germany) · 2026
    Article
  9. Article
  10. Article
  11. Genotypic Analysis ofInternational journal of molecular sciences · 2026
    Article
  12. Article
  13. Article
  14. Fifteen-minute consultation: Threadworm in children.Archives of disease in childhood. Education and practice edition · 2026
    Article
  15. Pinworm (Frontiers in public health · 2026
    Review
  16. Article
  17. Observational
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Sebastian WendtInstitute of Medical Microbiology and Epidemiology of Infectious Diseases, Leipzig University Hospital; Interdisciplinary Centre for Infectious Diseases (ZINF), Leipzig University Hospital; Department of Gastroenterology, Division of Infectious Diseases and Tropical Medicine, Leipzig University Hospital; Department of Gastroenterology, Leipzig University Hospital.
Henning Trawinski
Stefan Schubert
Arne C Rodloff
Joachim Mössner
Christoph Lübbert
University Hospital Leipzig · DELeipzig University · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSymptomatic infection with pinworm (Enterobius vermicularis), a human pathogen, is clinically relevant in Germany, with an estimated prevalence in childhood of 2-20%. Enterobiasis can cause major mental distress. There is little systematically verified knowledge on the treatment of this condition, and there is no corresponding German guideline. This review is, therefore, intended as a summary of the current state of knowledge.

methodsThis review is based on pertinent publications retrieved by a selective search in PubMed for literature appearing from 1 January 1990 to 5 February 2019 and containing the search terms "enterobiasis," "oxyuriasis," "Enterobius vermicula- ris," "pinworm," and "threadworm."

resultsMore than one billion people worldwide are thought to be infected with pinworm. Estimates of its prevalence among kindergarten and primary-school pupils in Europe are generally near 20%. Infants (<2 years of age), adolescents (>14 years of age), and adults are only sporadically affected. The main risk factors are age 4-11 years, uncontrolled anus-finger-mouth contact, nail-biting (onychophagia/peri- onychophagia), unsupervised body hygiene, and poor compliance with basic hand hygiene. No large-scale, randomized, controlled trials of treatment are available. The approved antihelminthic agents are mebendazole, pyrantel embonate, and pyrvinium embonate (success rates up to >90%). For recurrent infections, prolonged treatment for up to 16 weeks (a "pulse scheme") is recommended.

conclusionIn nearly all cases, antihelminthic treatment along with attention to hygienic measures can successfully eradicate pinworm infection and prevent recurrence and autoinfection. The involvement of all persons living in the patient's house- hold, including sexual partners, is a prerequisite to the lasting success of treatment.

Indexed as

EnterobiasisAdolescentAnimalsChildChild, PreschoolEnterobiusEuropeGermanyHumansHygieneInfant

Identifiers

PMID31064642
PMCPMC6522669
OpenAlexW2924650958

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.