Evidence map›Paper›PMID 31064340›Full record

ArticleBMC nephrology2019

Chronic kidney disease and HIV in the era of antiretroviral treatment: findings from a 10-year cohort study in a west African setting.

Nongodo Firmin Kaboré, Armel Poda, Jacques Zoungrana, Ollo Da, Laura Ciaffi, Aoua Semdé, Issouf Yaméogo, Adrien B Sawadogo, Eric Delaporte, Nicolas Meda and 2 more

Open access · goldAbstract read
In one paragraph

Article in BMC nephrology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
4.7field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 45 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Nongodo Firmin KaboréDepartment of Clinical Research, Centre MURAZ, Nongodo Firmin KABORE, Bobo-Dioulasso, BP 808, Burkina Faso. firmin.kabore@centre-muraz.bf.ORCID 0000-0002-3462-6568
Armel PodaDepartment of Infectious Diseases, University Hospital Souro Sanou, Bobo-Dioulasso, Burkina Faso.
Jacques ZoungranaDepartment of Infectious Diseases, University Hospital Souro Sanou, Bobo-Dioulasso, Burkina Faso.
Ollo DaBiochemistry Department, University Hospital Souro Sanou, Bobo-Dioulasso, Burkina Faso.
Laura CiaffiUnité Mixte Internationale 233, Institut de Recherche pour le Développement, U1175-Inserm, University of Montpellier, Montpellier, France.
Aoua SemdéDepartment of nephrology, University Hospital Souro Sanou, Bobo-Dioulasso, Burkina Faso.
Issouf YaméogoDepartment of Infectious Diseases, University Hospital Souro Sanou, Bobo-Dioulasso, Burkina Faso.
Adrien B SawadogoDepartment of Infectious Diseases, University Hospital Souro Sanou, Bobo-Dioulasso, Burkina Faso.
Eric DelaporteUnité Mixte Internationale 233, Institut de Recherche pour le Développement, U1175-Inserm, University of Montpellier, Montpellier, France.
Nicolas MedaUniversité Ouaga 1 Pr Joseph Ki-Zerbo, Ouagadougou, Burkina Faso.
Sophie LimouCentre de Recherche en Transplantation et Immunologie (CRTI) UMR1064, Inserm, Université de Nantes, Nantes, France.
Amandine CournilUnité Mixte Internationale 233, Institut de Recherche pour le Développement, U1175-Inserm, University of Montpellier, Montpellier, France.
Nazi Boni University · BFInserm · FRCentre Muraz · BFÉcole Centrale de Nantes · FRUniversité Joseph Ki-Zerbo · BF

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIt has been reported that people living with HIV in West Africa exhibited the highest risks for chronic kidney disease (CKD) in the world. Here, we aimed at determining the CKD frequency and changes in kidney function during antiretroviral treatment (ART) in a large cohort of HIV-patients followed in Burkina Faso.

methodsWe included ART-naive adults who initiated ART at the Day Care Unit of the Souro Sanou University Hospital between 01/01/2007 and 12/31/2016. We assessed the estimated glomerular filtration rate (eGFR) by serum creatinine using the Modification of Diet in Renal Disease (MDRD) equation. Following the K/DOQI recommendations, CKD was defined as eGFR < 60 ml/min/1.73m

resultsThree thousand, one hundred and thirty-eight patients (72% women) were followed for a median (IQR) of 4.5(2.2-6.9) years. At baseline, median eGFR (IQR) was 110.7(94.4-128.4) ml/min/1.73m

conclusionsOur findings do not confirm the high risk of CKD reported in previous studies of West Africans with HIV, but support the recommendations for early initiation of ART and close kidney function monitoring in patients with HBP or aged ≥40 yr.

Indexed as

AbacavirAdultAge FactorsAnti-HIV AgentsBurkina FasoCohort StudiesCreatinineDidanosineDideoxynucleosidesFemaleFollow-Up StudiesGlomerular Filtration RateHIV InfectionsHumansHypertensionIncidenceAbacavirAnti-HIV AgentsCreatinineDidanosineDideoxynucleosidesStavudineTenofovirZidovudineAfricaAntiretroviral treatmentBurkina FasoCKDEpidemiologyHIV

Identifiers

PMID31064340
PMCPMC6505177
OpenAlexW2947487766

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.