Evidence map›Paper›PMID 31064206›Full record

ArticleEthnicity & health2021

Developmental timing of initial racial discrimination exposure is associated with cardiovascular health conditions in adulthood.

Adolfo G Cuevas, Thao Ho, Justin Rodgers, Danielle DeNufrio, Lindsey Alley, Jennifer Allen, David R Williams

Abstract read
In one paragraph

Article in Ethnicity & health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Racial/Ethnic Discrimination and Cardiometabolic Diseases: A Systematic Review.Journal of racial and ethnic health disparities · 2024
    Pooled it
  2. Article
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  13. Integrating time into stigma and health research.Nature reviews psychology · 2022
    Review
  14. Article
  15. Article
  16. Article
  17. Review
  18. Social Determinants of Placental Health and Future Disease Risks for Babies.Obstetrics and gynecology clinics of North America · 2020
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adolfo G CuevasDepartment of Community Health, Tufts University, Medford, MA, USA.
Thao HoDepartment of Community Health, Tufts University, Medford, MA, USA.
Justin RodgersDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.
Danielle DeNufrioDepartment of Public Health and Community Medicine, Tufts' School of Medicine, Boston, MA, USA.
Lindsey AlleyHealthInsight Oregon, Portland, OR, USA.
Jennifer AllenDepartment of Community Health, Tufts University, Medford, MA, USA.
David R WilliamsDepartment of Social and Behavioral Sciences, Harvard T.H. Chan School of Public Health, Boston, MA, USA.

Funding

WORD PROCESSING CENTER--COREP30CA006927 · NCI · RESEARCH INST OF FOX CHASE CAN CTR · PI Margaret von Mehren · 1985 to 2026
$138.8M
CTSA Institutional Mentored Career Development Program (KL2)KL2TR002545 · NCATS · TUFTS UNIVERSITY BOSTON · PI FREUND, KAREN · 2018 to 2022
$5.0M
NCATS NIH HHS KL2 TR002545NCI NIH HHS P30 CA006927
6 · The paper itself

Abstract

objectiveTo examine the association between developmental timing of initial exposure to racial discrimination and cardiovascular health conditions.

designUsing data from the 1995 Detroit Area Study, logistic and negative binomial regression models were used to assess the association between timing of initial exposure to racial/ethnic discrimination, classified as early childhood (0-7), childhood (8-12), adolescence (13-19), and adulthood (>19), on physician-diagnosed cardiovascular health conditions during adulthood. Each analysis adjusted for age, gender, race/ethnicity, income, education, marital status, health-related behaviors, and pre-existing health conditions.

resultsOf the 1,106 participants in the final sample, 520 identified as White and 586 identified as Black. Over half (64%) of the sample experienced at least one major cardiovascular health event at the time of the study, with 39% reporting two or more events. Results from logistic regression models showed that initial exposure to racial discrimination during early childhood was associated with a 2.96 (95%CI:1.15, 7.83) times greater odds of having any cardiovascular-related health condition later in life compared to individuals who reported no discrimination. Results from negative binomial regression models demonstrated that individuals who reported initial exposure to racial discrimination during early childhood and adolescence had a CVD incidence rate that was 1.63 (95%CI:1.11, 2.38) and 1.37 (95%CI:1.10, 1.69) times higher than individuals who reported no discrimination.

conclusionInitial exposure to racial discrimination in early childhood and adolescence may increase the risk of cardiovascular conditions later in life. Clinicians and researchers should consider racial discrimination during childhood as a possible risk factor for illness and disease.

Indexed as

Cardiovascular DiseasesRacismAdolescentAdultChild, PreschoolEthnicityHumansIncomeRisk Factorscardiovascular healthchildhood adversitydevelopmental traumaracial discriminationself-rated health

Identifiers

PMID31064206
PMCPMC7026859

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.