Evidence map›Paper›PMID 31064097›Full record

ArticleInternational journal of molecular sciences2019

Monocyte Chemoattractant Protein-1, a Possible Biomarker of Multiorgan Failure and Mortality in Ventilator-Associated Pneumonia.

Yia-Ting Li, Yao-Chen Wang, Hsiang-Lin Lee, Su-Chin Tsao, Min-Chi Lu, Shun-Fa Yang

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.3field-weighted citation impact, top 20% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 21 citations in OpenAlex.

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  10. LIPS and PaOMediators of inflammation · 2024
    Observational
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Yia-Ting LiInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. miki2700@gmail.com.
Yao-Chen WangDivision of Pulmonary Medicine, Department of Internal Medicine, Chung Shan Medical University Hospital, Taichung 402, Taiwan. wang5717@ms21.hinet.net.
Hsiang-Lin LeeInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. s31079@gmail.com.
Su-Chin TsaoDepartment of Nursing, Chung Shan Medical University Hospital, Taichung 402, Taiwan. suchin311@gmail.com.
Min-Chi LuDivision of Infectious Diseases, Department of Internal Medicine, China Medical University Hospital, Taichung 404, Taiwan. luminchi@gmail.com.
Shun-Fa YangInstitute of Medicine, Chung Shan Medical University, Taichung 402, Taiwan. ysf@csmu.edu.tw.ORCID 0000-0002-0365-7927
Chung Shan Medical University Hospital · TWChina Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ventilator-associated pneumonia (VAP) leads to increased patients' mortality and medical expenditure. Monocyte chemoattractant protein-1 (MCP-1) plays a role in the pathogenesis of lung inflammation and infection. Therefore, the plasma concentration of MCP-1 was assessed and correlated with the clinical course in VAP patients. This retrospective observational study recruited 45 healthy volunteers, 12 non-VAP subjects, and 30 VAP patients. The diagnostic criteria for VAP were based on the American Thoracic Society guidelines, and the level of plasma MCP-1 was determined by ELISA. Plasma MCP-1 concentration was significantly elevated in the acute stage in VAP patients when compared with the control (

Indexed as

BiomarkersChemokine CCL2FemaleHumansMaleMiddle AgedMultiple Organ FailurePneumonia, Ventilator-AssociatedBiomarkersCCL2 protein, humanChemokine CCL2Monocyte chemoattractant protein-1mortalityorgan failureventilator-associated pneumonia

Identifiers

PMID31064097
PMCPMC6539645
OpenAlexW2943750954

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.