Evidence map›Paper›PMID 31063702›Full record

ArticleFASEB journal : official publication of the Federation of American Societies for Experimental Biology2019

Cytochrome c oxidase dysfunction enhances phagocytic function and osteoclast formation in macrophages.

Rajesh Angireddy, Hasan Raza Kazmi, Satish Srinivasan, Li Sun, Jameel Iqbal, Serge Y Fuchs, Manti Guha, Takashi Kijima, Tony Yuen, Mone Zaidi and 1 more

Open access · greenAbstract read
In one paragraph

Article in FASEB journal : official publication of the Federation of American Societies for Experimental Biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 44 citations in OpenAlex.

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  7. Bmi-1 plays an important role in preventing bone aging by regulating the bone microenvironment.International journal of clinical and experimental pathology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 1 country.

Rajesh AngireddyDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Hasan Raza KazmiDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Satish SrinivasanDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Li SunThe Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Jameel IqbalThe Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Serge Y FuchsDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Manti GuhaDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Takashi KijimaDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
Tony YuenThe Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Mone ZaidiThe Mount Sinai Bone Program, Department of Medicine, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Narayan G AvadhaniDepartment of Biomedical Sciences, School of Veterinary Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.
University of Pennsylvania · USIcahn School of Medicine at Mount Sinai · USRoche (United States) · US

Funding

UPR, interferon signaling and tumorigenesisP01CA165997 · NCI · UNIVERSITY OF PENNSYLVANIA · PI KOUMENIS, CONSTANTINOS · 2013 to 2023
$10.9M
Role of HOS in Cell Transformation and ApoptosisR01CA092900 · NCI · UNIVERSITY OF PENNSYLVANIA · PI FUCHS, SERGE Y · 2001 to 2021
$5.3M
Thyrotropin Receptor, Thyrotropin and Mechanisms of Bone LossR01DK113627 · NIDDK · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI DAVIES, TERRY FRANCIS, IQBAL, JAMEEL Z · 2017 to 2020
$2.8M
NCI NIH HHS P01 CA165997NCI NIH HHS R01 CA092900NIDDK NIH HHS R01 DK113627
6 · The paper itself

Abstract

The mitochondria-to-nucleus retrograde signaling (MtRS) pathway aids in cellular adaptation to stress. We earlier reported that the Ca

Indexed as

AnimalsCell DifferentiationElectron Transport Complex IVGene Knockdown TechniquesMacrophagesMembrane ProteinsMiceMice, Inbred BALB CMice, KnockoutMitochondriaOsteoclastsOsteogenesisPhagocytosisRAW 264.7 CellsReactive Oxygen SpeciesRNA, Small InterferingElectron Transport Complex IVMembrane ProteinsMpv17 protein, mouseReactive Oxygen SpeciesRNA, Small Interferinginflammatory cytokinesreactive oxygen speciesrespiratory changesretrograde signalingSubunit IVi1

Identifiers

PMID31063702
PMCPMC6662975
OpenAlexW2944765338

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.