Observational studyPloS one2019
Use of prehospital qSOFA in predicting in-hospital mortality in patients with suspected infection: A retrospective cohort study.
Observational study in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
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Who cites it
11 citing papers in PubMed.
- Prehospital qSOFA Is Associated with 30-Day Mortality Within Emergency Department Triage Strata in Ambulance-Transported Adults with Suspected Infection: An Exploratory Three-Year Retrospective Cohort Study.Journal of clinical medicine · 2026Article
- Prehospital pulse pressure and mortality of septic shock patients cared for by a mobile intensive care unit.BMC emergency medicine · 2023Article
- Article
- Is Prehospital Assessment of qSOFA Parameters Associated with Earlier Targeted Sepsis Therapy? A Retrospective Cohort Study.Journal of clinical medicine · 2022Article
- Association between prehospital shock index variation and 28-day mortality among patients with septic shock.BMC emergency medicine · 2022Article
- Severity Scores in COVID-19 Pneumonia: a Multicenter, Retrospective, Cohort Study.Journal of general internal medicine · 2021Article
- The sensitivity of qSOFA calculated at triage and during emergency department treatment to rapidly identify sepsis patients.Scientific reports · 2020Observational
- Institution-Specific Machine Learning Models for Prehospital Assessment to Predict Hospital Admission: Prediction Model Development Study.JMIR medical informatics · 2020Article
- Pre-Hospital Lactatemia Predicts 30-Day Mortality in Patients with Septic Shock-Preliminary Results from the LAPHSUS Study.Journal of clinical medicine · 2020Article
- Screening strategies to identify sepsis in the prehospital setting: a validation study.CMAJ : Canadian Medical Association journal = journal de l'Association medicale canadienne · 2020Article
- Relationship between the prehospital quick Sequential Organ Failure Assessment and prognosis in patients with sepsis or suspected sepsis: a population-based ORION registry.Acute medicine & surgeryArticle
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Authors and funding
5 authors.
Funding
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Abstract
backgroundThe quick sequential organ failure assessment (qSOFA) score has recently been introduced to the emergency department (ED) and wards, and it predicted a higher number of deaths among patients with sepsis compared with baseline risk. However, studies about the application of the qSOFA score are limited in prehospital settings. Thus, this study aimed to assess the performance of prehospital qSOFA score in predicting the risk of mortality among patients with infection.
methodsThis single center, retrospective cohort study was conducted in a Japanese tertiary care teaching hospital between April 2016 and March 2017. We enrolled all consecutive adult patients transported to the hospital by ambulance and admitted to the ED due to a suspected infection. We calculated the prehospital qSOFA score using the first vital sign obtained at the scene by emergency medical service (EMS) providers. The primary outcome was in-hospital mortality. The Cox proportional hazards model was used to assess the association between prehospital qSOFA positivity and in-hospital mortality.
resultsAmong the 925 patients admitted to the ED due to a suspected infection, 51.1% (473/925) were prehospital qSOFA-positive and 48.9% (452/925) were prehospital qSOFA-negative. The in-hospital mortality rates were 14.0% (66/473) in prehospital qSOFA-positive patients and 6.0% (27/452) in prehospital qSOFA-negative patients. The Cox proportional hazard regression model revealed a strong association between prehospital qSOFA score and in-hospital mortality (adjusted hazard ratio: 2.41, 95% confidence interval: 1.51-3.98; p <0.01).
conclusionsAmong the patients with suspected infection who were admitted at the ED, a strong association was observed between the prehospital qSOFA score and in-hospital mortality. In order to use this score in clinical practice, future study is necessary to evaluate how infection is suspected in the prehospital arena.
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