ArticlePloS one2019
Using fecal microbiota as biomarkers for predictions of performance in the selective breeding process of pedigree broiler breeders.
Article in PloS one, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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Who cites it
29 citing papers in PubMed.
- Sex and social group altered the gut microbiome and fecal metabolome in the critically endangered Yangtze finless porpoise (Current zoology · 2026Article
- The hologenome concept and its implications for animal breeding in the multi-omics Era.Genetics and molecular biology · 2026Article
- Multidimensional regulatory mechanisms of chicken immunity: focus on viral infection, intestinal microbiota and heat stress.Frontiers in veterinary science · 2026Review
- Rumen microbiome profiles of dairy cattle are affected by the presence of, and vaccination against, the abomasal parasitic nematode Ostertagia ostertagi.Scientific reports · 2025Article
- The chicken gut microbiome in conventional and alternative production systems.Journal of animal science and biotechnology · 2025Review
- Effect of calf separation on gut microbiome and fecal metabolome of mother in the captive Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis).International microbiology : the official journal of the Spanish Society for Microbiology · 2025Article
- Chemical Composition, Cytotoxicity, and Encapsulation of Lavender Essential Oil (Molecules (Basel, Switzerland) · 2025Article
- Lack of consistency in poultry dust microbial taxa associated with high and low-performing commercial broiler flocks.Poultry science · 2025Article
- Seasonal Breeding Alters Fecal Microbiota and Metabolome in the Male Captive Yangtze Finless Porpoise (Ecology and evolution · 2025Article
- Physiological function of gut microbiota and metabolome on successful pregnancy and lactation in the captive Yangtze finless porpoise (Neophocaena asiaeorientalis asiaeorientalis)†.Biology of reproduction · 2024Article
- Detection and characterization of Campylobacter in air samples from poultry houses using shot-gun metagenomics - a pilot study.BMC microbiology · 2024Article
- Host genetics and gut microbiota synergistically regulate feed utilization in egg-type chickens.Journal of animal science and biotechnology · 2024Article
- Effects of Traditional Chinese Herbal Feed Additive on Production Performance, Egg Quality, Antioxidant Capacity, Immunity and Intestinal Health of Laying Hens.Animals : an open access journal from MDPI · 2023Article
- Dynamic Changes in the Gut Microbiota and Metabolites during the Growth of Hainan Wenchang Chickens.Animals : an open access journal from MDPI · 2023Article
- Application of Baltic Pine (Plants (Basel, Switzerland) · 2023Article
- Dynamic Changes in the Gut Microbial Community and Function during Broiler Growth.Microbiology spectrum · 2022Article
- Development and Evaluation of a Commercial Direct-Fed Microbial (ZymosporeAnimals : an open access journal from MDPI · 2022Article
- Ileal and cecal microbiota response toFrontiers in physiology · 2022Article
- Effect of DietaryFrontiers in veterinary science · 2022Article
- Metformin modulates the gut microbiome in broiler breeder hens.Frontiers in physiology · 2022Article
Corrections and comments
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Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Much work has been dedicated to identifying members of the microbial gut community that have potential to augment the growth rate of agricultural animals including chickens. Here, we assessed any correlations between the fecal microbiome, a proxy for the gut microbiome, and feed efficiency or weight gain at the pedigree chicken level, the highest tier of the production process. Because selective breeding is conducted at the pedigree level, our aim was to determine if microbiome profiles could be used to predict feed conversion or weight gain in order to improve selective breeding. Using 16s rRNA amplicon sequencing, we profiled the microbiomes of high and low weight gain (WG) birds and good and poor feed efficient (FE) birds in two pedigree lineages of broiler chickens. We also aimed to understand the dynamics of the microbiome with respect to maturation. A time series experiment was conducted, where fecal samples of chickens were collected at 6 points of the rearing process and the microbiome of these samples profiled. We identified OTUs differences at different taxonomic levels in the fecal community between high and low performing birds within each genetic line, indicating a specificity of the microbial community profiles correlated to performance factors. Using machine-learning methods, we built a classification model that could predict feed conversion performance from the fecal microbial community. With respect to maturation, we found that the fecal microbiome is dynamic in early life but stabilizes after 3 weeks of age independent of lineage. Our results indicate that the fecal microbiome profile can be used to predict feed conversion, but not weight gain in these pedigree lines. From the time series experiments, it appears that these predictions can be evaluated as early as 20 days of age. Our data also indicates that there is a genetic factor for the microbiome profile.
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