ArticleEpidemiology and infection2019
Zoonotic approach to Shiga toxin-producing Escherichia coli: integrated analysis of virulence and antimicrobial resistance in ruminants and humans.
Article in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 36 citations in OpenAlex.
- First Pandemic blaCTX-M-8-Producing ST224 E. coli in Brazilian Sheep: Resistance and Genomic Traits.EcoHealth · 2026Article
- Shiga toxin-producingMicrobiology and molecular biology reviews : MMBR · 2025Review
- Co-resistance and plasmid-mediated co-dissemination of florfenicol and azithromycin resistance in non-O157 Shiga toxin-producing Escherichia coli from cattle in Xinjiang, China.BMC microbiology · 2025Article
- Effects of Metabolites of Lactobacillus casei on Expression and Neutralization of Shiga Toxin by Enterohemorrhagic Escherichia coli.Probiotics and antimicrobial proteins · 2025Article
- Evaluation of Single and Multi-Strain Probiotics with Gentamicin AgainstMicroorganisms · 2025Article
- Prevalence of Shiga-ToxigenicMicroorganisms · 2025Article
- Isolation of Shiga toxin-producing Escherichia coli from sheep faecal samples: bacteriological findings.Access microbiology · 2025Article
- Molecular Detection of Shiga Toxin-ProducingInternational journal of microbiology · 2024Article
- Multidrug-resistant Shiga toxin-producing Escherichia coli and hybrid pathogenic strains of bovine origin.Veterinary research communications · 2023Article
- Characteristics of Shiga Toxin-ProducingToxins · 2023Article
- Prevalence and Virulent Gene Profiles of Sorbitol Non-Fermenting Shiga Toxin-ProducingTropical medicine and infectious disease · 2022Article
- Bacteriocin-ProducingMicroorganisms · 2022Article
- Prevalence and Molecular Characterisation of Extended-Spectrum Beta-Lactamase-Producing Shiga Toxin-ProducingPathogens (Basel, Switzerland) · 2022Article
- PathogenicAntibiotics (Basel, Switzerland) · 2022Article
- Potential Zoonotic Pathovars of DiarrheagenicMicroorganisms · 2021Article
- Antimicrobial Resistance ofAnimals : an open access journal from MDPI · 2021Article
- Molecular detection of Shiga toxin-producing Escherichia coli (STEC) O157 in sheep, goats, cows and buffaloes.Molecular biology reports · 2021Article
- Molecular Detection of Antibiotic Resistance Genes in Shiga Toxin-ProducingAntibiotics (Basel, Switzerland) · 2021Article
- Antimicrobial Resistance of Non-O157 Shiga Toxin-ProducingAntibiotics (Basel, Switzerland) · 2021Article
- Genomic Insights Into Clinical Shiga Toxin-ProducingFrontiers in microbiology · 2021Article
Corrections and comments
- Erratum issued
Authors and funding
6 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
In 2014-2016, we conducted a cross-sectional survey in 115 sheep, 104 beef and 82 dairy cattle herds to estimate Shiga toxin-producing Escherichia coli (STEC) prevalence, and collected data on human clinical cases of infection. Isolates were characterised (stx1, stx2, eae, ehxA) and serogroups O157 and O111 identified by PCR, and their antimicrobial resistance (AMR) profiles were determined by broth microdilution. STEC were more frequently isolated from beef cattle herds (63.5%) and sheep flocks (56.5%) than from dairy cattle herds (30.5%) (P < 0.001). A similar but non-significant trend was observed for O157:H7 STEC. In humans, mean annual incidence rate was 1.7 cases/100 000 inhabitants for O157 STEC and 4.7 for non-O157 STEC, but cases concentrated among younger patients. Distribution of virulence genes in STEC strains from ruminants differed from those from human clinical cases. Thus, stx2 was significantly associated with animal STEC isolates (O157 and non-O157), ehxA to ruminant O157 STEC (P = 0.004) and eae to human non-O157 STEC isolates (P < 0.001). Resistance was detected in 21.9% of human and 5.2% of animal O157 STEC isolates, whereas all non-O157 isolates were fully susceptible. In conclusion, STEC were widespread in ruminants, but only some carried virulence genes associated with severe disease in humans; AMR in ruminants was low but profiles were similar to those found in human isolates.
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