Evidence map›Paper›PMID 31063101›Full record

ArticleEpidemiology and infection2019

Developing influenza and respiratory syncytial virus activity thresholds for syndromic surveillance in England.

S E Harcourt, R A Morbey, G E Smith, P Loveridge, H K Green, R Pebody, J Rutter, F A Yeates, G Stuttard, A J Elliot

Open access · hybridAbstract read
In one paragraph

Article in Epidemiology and infection, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 15 citations in OpenAlex.

  1. Determining the timing of respiratory syncytial virus (RSV) epidemics: a systematic review, 2016 to 2021; method categorisation and identification of influencing factors.Euro surveillance : bulletin Europeen sur les maladies transmissibles = European communicable disease bulletin · 2024
    Pooled it
  2. Article
  3. Observational
  4. Article
  5. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

S E HarcourtReal-time Syndromic Surveillance Team,Field Service,National Infection Service,Public Health England,Birmingham,UK.ORCID 0000-0002-2278-9642
R A MorbeyReal-time Syndromic Surveillance Team,Field Service,National Infection Service,Public Health England,Birmingham,UK.
G E SmithReal-time Syndromic Surveillance Team,Field Service,National Infection Service,Public Health England,Birmingham,UK.ORCID 0000-0002-4257-0568
P LoveridgeReal-time Syndromic Surveillance Team,Field Service,National Infection Service,Public Health England,Birmingham,UK.
H K GreenReal-time Syndromic Surveillance Team,Field Service,National Infection Service,Public Health England,Birmingham,UK.
R PebodyRespiratory Diseases Department,National Infection Service,Public Health England,London,UK.ORCID 0000-0002-9069-2885
J RutterNHS Pathways,NHS Digital,Leeds,UK.
F A YeatesAdvanced,Ashford,UK.
G StuttardNHS England,Birmingham,UK.
A J ElliotReal-time Syndromic Surveillance Team,Field Service,National Infection Service,Public Health England,Birmingham,UK.
Public Health England · GBAshford Hospital · GBBirmingham Community Healthcare NHS Trust · GBNHS Digital · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Influenza and respiratory syncytial virus (RSV) are common causes of respiratory tract infections and place a burden on health services each winter. Systems to describe the timing and intensity of such activity will improve the public health response and deployment of interventions to these pressures. Here we develop early warning and activity intensity thresholds for monitoring influenza and RSV using two novel data sources: general practitioner out-of-hours consultations (GP OOH) and telehealth calls (NHS 111). Moving Epidemic Method (MEM) thresholds were developed for winter 2017-2018. The NHS 111 cold/flu threshold was breached several weeks in advance of other systems. The NHS 111 RSV epidemic threshold was breached in week 41, in advance of RSV laboratory reporting. Combining the use of MEM thresholds with daily monitoring of NHS 111 and GP OOH syndromic surveillance systems provides the potential to alert to threshold breaches in real-time. An advantage of using thresholds across different health systems is the ability to capture a range of healthcare-seeking behaviour, which may reflect differences in disease severity. This study also provides a quantifiable measure of seasonal RSV activity, which contributes to our understanding of RSV activity in advance of the potential introduction of new RSV vaccines.

Indexed as

Sentinel SurveillanceEnglandHumansInfluenza, HumanReferral and ConsultationRespiratory Syncytial Virus InfectionsTelemedicineInfluenzamoving epidemic methodrespiratory syncytial virussyndromic surveillancethresholds

Identifiers

PMID31063101
PMCPMC6518470
OpenAlexW2923465895

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.