ArticleRadiology2019
Tracking Stem Cell Implants in Cartilage Defects of Minipigs by Using Ferumoxytol-enhanced MRI.
Abstract read
In one paragraph
Article in Radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Insights into vitamin C in musculoskeletal physiology and disorders: mechanisms and translational perspectives.Frontiers in immunology · 2026Review
- Ferumoxytol promotes haematopoietic stem cell post-injury regeneration as a reactive oxygen species scavenger.Nature nanotechnology · 2025Article
- MRI monitoring of USPIO-labeled BMSCs combined with alginate scaffold for cartilage defect repair.Frontiers in bioengineering and biotechnology · 2025Article
- Unveiling the next generation of MRI contrast agents: current insights and perspectives on ferumoxytol-enhanced MRI.National science review · 2024Review
- Review
- MRI/PAI Dual-modal Imaging-guided Precise Tracking of Bone Marrow-derived Mesenchymal Stem Cells Labeled with Nanoparticles for Treating Liver Cirrhosis.Journal of clinical and translational hepatology · 2023Article
- Ferumoxytol-Enhanced MRI in Children and Young Adults: State of the Art.AJR. American journal of roentgenology · 2023Article
- Article
- MegaPro, a clinically translatable nanoparticle forTheranostics · 2023Article
- Extracellular magnetic labeling of biomimetic hydrogel-induced human mesenchymal stem cell spheroids with ferumoxytol for MRI tracking.Bioactive materials · 2023Article
- Vascular injury of immature epiphyses impair stem cell engraftment in cartilage defects.Scientific reports · 2022Article
- Human integrin α10β1-selected mesenchymal stem cells home to cartilage defects in the rabbit knee and assume a chondrocyte-like phenotype.Stem cell research & therapy · 2022Article
- Mechanoporation enables rapid and efficient radiolabeling of stem cells for PET imaging.Scientific reports · 2022Article
- In vivo imaging of nanoparticle-labeled CAR T cells.Proceedings of the National Academy of Sciences of the United States of America · 2022Article
- Applications of Magnetic Particle Imaging in Biomedicine: Advancements and Prospects.Frontiers in physiology · 2022Review
- Repurposing ferumoxytol: Diagnostic and therapeutic applications of an FDA-approved nanoparticle.Theranostics · 2022Review
- High-Resolution Imaging for the Analysis and Reconstruction of 3D Microenvironments for Regenerative Medicine: An Application-Focused Review.Bioengineering (Basel, Switzerland) · 2021Review
- Fusogenic liposome-enhanced cytosolic delivery of magnetic nanoparticles.RSC advances · 2021Article
- Allogeneic mesenchymal stromal cells for cartilage regeneration: A review of in vitro evaluation, clinical experience, and translational opportunities.Stem cells translational medicine · 2021Review
- Ascorbic Acid and Iron Supplement Treatment Improves Stem Cell-Mediated Cartilage Regeneration in a Minipig Model.The American journal of sports medicine · 2021Article
Corrections and comments
- Commented on by
- Commented on by
Authors and funding
12 authors.
Ashok J TheruvathFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).ORCID 0000-0003-0764-6800
Hossein NejadnikFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).ORCID 0000-0003-1249-0724
Olga LenkovFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).
Ketan YerneniFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).ORCID 0000-0003-2373-005X
Kai LiFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).ORCID 0000-0003-1664-5439
Lara KuntzFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).ORCID 0000-0002-4942-7529
Cody WoltermanFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).
Jutta TuebelFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).
Rainer BurgkartFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).ORCID 0000-0002-9107-4229
Tie LiangFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).
Stephen FeltFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).ORCID 0000-0001-7030-717X
Heike E Daldrup-LinkFrom the Department of Radiology and Molecular Imaging Program at Stanford (MIPS) (A.J.T., H.N., O.L., K.Y., K.L., L.K., C.W., T.L., H.E.D.), Department of Comparative Medicine (S.F.), and Department of Pediatrics (H.E.D.), Stanford University School of Medicine, 725 Welch Rd, Room 1665, Stanford, CA 94305-5654; Department of Diagnostic and Interventional Radiology, University Medical Center Mainz, Mainz, Germany (A.J.T.); and Department of Orthopedics and Sportorthopedics, Klinikum Rechts der Isar, Technical University of Munich, Munich, Germany (L.K., J.T., R.B.).ORCID 0000-0002-4929-819X
Funding
Monitoring of Stem Cell Engraftment in Arthritic Joints with MR ImagingR01AR054458 · NIAMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI DALDRUP-LINK, HEIKE ELIZABETH · 2008 to 2021
$6.7MPersonalized Whole Body Staging for Children with Cancer: A Solution to the Conundrum of Long-Term Side Effects from CT and PET/CT ScansR01HD081123 · NICHD · STANFORD UNIVERSITY · PI DALDRUP-LINK, HEIKE ELIZABETH · 2015 to 2019
$2.5MNIAMS NIH HHS R01 AR054458NICHD NIH HHS R01 HD081123
Abstract
Background Cartilage repair outcomes of matrix-associated stem cell implants (MASIs) in patients have been highly variable. Conventional MRI cannot help distinguish between grafts that will and grafts that will not repair the underlying cartilage defect until many months after the repair. Purpose To determine if ferumoxytol nanoparticle labeling could be used to depict successful or failed MASIs compared with conventional MRI in a large-animal model. Materials and Methods Between January 2016 and December 2017, 10 Göttingen minipigs (
Indexed as
Contrast MediaFerrosoferric OxideAnimalsCartilage, ArticularCartilage DiseasesDisease Models, AnimalMagnetic Resonance ImagingStem Cell TransplantationSwineTreatment OutcomeContrast MediaFerrosoferric Oxide
Identifiers
What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.