Observational studyThe Journal of urology2019
Patient Characteristics Associated with More Bother from Lower Urinary Tract Symptoms.
Observational study in The Journal of urology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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The trial behind it
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Who cites it
15 citing papers in PubMed.
- Comparison of 100 U With 200 U of Intradetrusor OnabotulinumToxinA for Nonneurogenic Urgency Incontinence.Female pelvic medicine & reconstructive surgery · 2021Trial
- Trial
- Cross-Sectional Associations of Depressive Symptoms, Anxiety Symptoms, and Emotional Support Seeking with Lower Urinary Tract Symptoms and Bladder Health.International urogynecology journal · 2025Article
- Pathways from Adverse Childhood Family Environment to Lower Urinary Tract Symptoms and Impact Among Women.Journal of women's health (2002) · 2025Article
- The association between depressive symptoms and lower urinary tract symptoms and impact among women: Investigating behavioural, cognitive and physiological pathways.British journal of health psychology · 2025Article
- Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN): An introduction to the Urinary Urgency Phenotyping Protocol LURN II.Neurourology and urodynamics · 2024Review
- The brain, gut, and bladder health nexus: A conceptual model linking stress and mental health disorders to overactive bladder in women.Neurourology and urodynamics · 2024Article
- Psychosocial Factors Associated with Lower Urinary Tract Symptoms One Year Postpartum.International journal of environmental research and public health · 2023Article
- Lower Urinary Tract Symptoms in Depression: A Review.Health psychology research · 2023Article
- Impact of Sleep Disturbance, Physical Function, Depression and Anxiety on Male Lower Urinary Tract Symptoms: Results from the Symptoms of Lower Urinary Tract Dysfunction Research Network (LURN).The Journal of urology · 2022Article
- Genetic background but not prostatic epithelial beta-catenin influences susceptibility of male mice to testosterone and estradiol-induced urinary dysfunction.American journal of clinical and experimental urology · 2021Article
- Relationship of symptom severity and bother in individuals seeking care for lower urinary tract symptoms.Neurourology and urodynamics · 2020Article
- Analyzing and Characterizing Why Men Seek Care for Lower Urinary Tract Symptoms.Current urology reports · 2020Review
- Undertreatment of overactive bladder among men with lower urinary tract symptoms in the United States: A retrospective observational study.Neurourology and urodynamics · 2020Observational
- Effect of electroacupuncture on diabetic neurogenic bladder: A randomized controlled trial protocol.Medicine · 2020Article
Corrections and comments
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Authors and funding
20 authors.
Funding
Abstract
purposeSome patients continue to have bothersome lower urinary tract symptoms despite treatment. We examined characteristics associated with bother from lower urinary tract symptoms in a prospective cohort. MATERIALS AND
methodsIn this 1-year prospective, observational cohort study we obtained data on patients with lower urinary tract symptoms who were seeking care at a total of 6 tertiary care centers in the United States. Participants answered the AUA-SI (American Urological Association Symptom Index) global urinary bother question at study entry and 12 months later. Multilevel logistic and linear regression was used to identify factors associated with worsening bother and bother at 12 months, respectively.
resultsOf the 756 participants 121 (16%) had worsened lower urinary tract symptom bother during the study period. When adjusted for other variables, worsened lower urinary tract symptom bother was more likely among men who were nonwhite (OR 1.79, 95% CI 0.94-3.40) or who had diabetes (OR 1.68, 95% CI 0.86-3.27) and among women with diabetes (OR 1.77, 95% CI 0.85-3.67), prior treatment of lower urinary tract symptoms (OR 2.58, 95% CI 1.22-5.46) or a higher depression level (OR 1.29, 95% CI 1.10-1.52). Baseline factors associated with more severe bother at 12 months in men included more severe bother at baseline, nonwhite race, worse urinary frequency and incontinence, and higher levels of stress (p <0.05). Among women more severe bother at baseline, urinary urgency and frequency, and worse physical function were associated with more severe bother at 12 months.
conclusionsUrinary symptom severity at baseline, race, depression and psychological stress were associated with the bother of lower urinary tract symptoms in a prospective cohort of men and women treated at tertiary care facilities. These findings may inform the clinical care of patients with bothersome lower urinary tract symptoms and direct providers to better prognosticate for patients with challenging lower urinary tract symptoms cases.
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