Evidence map›Paper›PMID 31062506›Full record

ArticleCatheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions2019

X-ray fused with MRI guidance of pre-selected transcatheter congenital heart disease interventions.

Elena K Grant, Joshua P Kanter, Laura J Olivieri, Russell R Cross, Adrienne Campbell-Washburn, Anthony Z Faranesh, Ileen Cronin, Karin S Hamann, Michael L O'Byrne, Michael C Slack and 2 more

Abstract read
In one paragraph

Article in Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 11 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 4 institutions in 1 country.

Elena K GrantDepartment of Cardiology, Children's National Medical Center, Washington, District of Columbia.ORCID https://orcid.org/0000-0002-7698-278X
Joshua P KanterDepartment of Cardiology, Children's National Medical Center, Washington, District of Columbia.
Laura J OlivieriDepartment of Cardiology, Children's National Medical Center, Washington, District of Columbia.
Russell R CrossDepartment of Cardiology, Children's National Medical Center, Washington, District of Columbia.
Adrienne Campbell-WashburnDivision of Intramural Research, Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Anthony Z FaraneshDivision of Intramural Research, Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Ileen CroninDepartment of Cardiology, Children's National Medical Center, Washington, District of Columbia.
Karin S HamannDepartment of Cardiology, Children's National Medical Center, Washington, District of Columbia.
Michael L O'ByrneDivison of Cardiology, The Children's Hospital of Philadelphia, Philadelphia, Pennsylvania.
Michael C SlackChildren's Heart Program, University of Maryland Children's Heart Program, Baltimore, Maryland.
Robert J LedermanDivision of Intramural Research, Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.ORCID https://orcid.org/0000-0003-1202-6673
Kanishka RatnayakaDivision of Intramural Research, Cardiovascular Branch, National Heart Lung and Blood Institute, National Institutes of Health, Bethesda, Maryland.
Children's National · USNational Institutes of Health · USChildren's Hospital of Philadelphia · USUniversity of Maryland, Baltimore · US

Funding

Real-time MRI guided cardiovascular interventionZIAHL005062 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2009 to 2025
$21.6M
Real-time cardiovascular MRI and co-registration technical developmentZIAHL006039 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI LEDERMAN, ROBERT J · 2010 to 2024
$10.3M
Innovative Technology for MRI Guided ProceduresZIAHL006213 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI CAMPBELL-WASHBURN, ADRIENNE · 2016 to 2025
$5.4M
Intramural NIH HHS ZIA HL006039NHLBI NIH HHS HHSN268201500001CNHLBI NIH HHS HHSN268201500001I
6 · The paper itself

Abstract

objectivesTo determine whether X-ray fused with MRI (XFM) is beneficial for select transcatheter congenital heart disease interventions.

backgroundComplex transcatheter interventions often require three-dimensional (3D) soft tissue imaging guidance. Fusion imaging with live X-ray fluoroscopy can potentially improve and simplify procedures.

methodsPatients referred for select congenital heart disease interventions were prospectively enrolled. Cardiac MRI data was overlaid on live fluoroscopy for procedural guidance. Likert scale operator assessments of value were recorded. Fluoroscopy time, radiation exposure, contrast dose, and procedure time were compared to matched cases from our institutional experience.

resultsForty-six patients were enrolled. Pre-catheterization, same day cardiac MRI findings indicated intervention should be deferred in nine patients. XFM-guided cardiac catheterization was performed in 37 (median age 8.7 years [0.5-63 years]; median weight 28 kg [5.6-110 kg]) with the following prespecified indications: pulmonary artery (PA) stenosis (n = 13), aortic coarctation (n = 12), conduit stenosis/insufficiency (n = 9), and ventricular septal defect (n = 3). Diagnostic catheterization showed intervention was not indicated in 12 additional cases. XFM-guided intervention was performed in the remaining 25. Fluoroscopy time was shorter for XFM-guided intervention cases compared to matched controls. There was no significant difference in radiation dose area product, contrast volume, or procedure time. Operator Likert scores indicated XFM provided useful soft tissue guidance in all cases and was never misleading.

conclusionsXFM provides operators with meaningful three-dimensional soft tissue data and reduces fluoroscopy time in select congenital heart disease interventions.

Indexed as

Cardiac CatheterizationMagnetic Resonance ImagingRadiography, InterventionalAdolescentAdultChildChild, PreschoolClinical Decision-MakingContrast MediaFemaleFluoroscopyHeart Defects, CongenitalHumansInfantMaleMiddle AgedContrast Mediadevice closurefusion imagingmagnetic resonance imagingtranscatheter

Identifiers

PMID31062506
PMCPMC6823111
OpenAlexW2944680573

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.