Evidence map›Paper›PMID 31062270›Full record

SynthesisJournal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract2019

Effect of Perioperative Nutritional Supplementation on Postoperative Complications-Systematic Review and Meta-Analysis.

Betty Zhang, Zainab Najarali, Leyo Ruo, Abdullah Alhusaini, Natalie Solis, Marlie Valencia, Maria Ines Pinto Sanchez, Pablo E Serrano

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Journal of gastrointestinal surgery : official journal of the Society for Surgery of the Alimentary Tract, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 7 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
35citing papers in PubMed, 7 pooled it
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

35 citing papers in PubMed, 7 syntheses or guidelines pooled it, 85 citations in OpenAlex.

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  7. Oral nutrition interventions in patients undergoing gastrointestinal surgery for cancer: A systematic literature review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2020
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Betty ZhangMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Zainab NajaraliMichael G. DeGroote School of Medicine, McMaster University, Hamilton, ON, Canada.
Leyo RuoDepartment of Oncology, McMaster University, Hamilton, ON, Canada.
Abdullah AlhusainiRoyal College of Surgeons in Ireland, Dublin, Ireland.
Natalie SolisDepartment of Surgery, McMaster University, Hamilton, ON, Canada.
Marlie ValenciaDepartment of Surgery, McMaster University, Hamilton, ON, Canada.
Maria Ines Pinto SanchezDepartment of Medicine, Division of Gastroenterology, McMaster University, Hamilton, ON, Canada.
Pablo E SerranoDepartment of Surgery, McMaster University, Hamilton, ON, Canada. serrano@mcmaster.ca.ORCID 0000-0002-3715-6880
McMaster University · CARoyal College of Surgeons in Ireland · IEUniversity of Toronto · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPerioperative carbohydrate loading, increased protein intake, and immunonutrition may decrease postoperative complications. Studies on the topic have led to controversial results.

methodsWe searched Medline, EMBASE, and CENTRAL up to August 2018 for randomized trials comparing the effect of perioperative nutritional supplements (intervention) versus control on postoperative complications in patients undergoing gastrointestinal cancer surgery. Secondary outcomes included infectious complications and length of hospital stay (LOS). Random effects model was used to estimate the pooled risk ratio (RR) of treatment effects. Pooled mean difference (MD) was used to compare LOS. Heterogeneity was assessed using I

resultsOf 3951 articles, we identified 56 trials (n = 6370). Perioperative nutrition was associated with a lower risk of postoperative complications (RR 0.74, 95% confidence interval (CI) 0.69-0.80); postoperative infections (RR 0.71, 95% CI 0.64-0.79, n = 4582); and postoperative non-infectious complications (RR 0.79, 95% CI 0.71-0.87, n = 4883). There were no significant heterogeneity outcomes analyzed (I

conclusionPerioperative nutritional optimization decreases the risk of postoperative infectious and non-infectious complications. It also decreases LOS in patients undergoing gastrointestinal cancer surgery, but these findings should be taken with caution given the high heterogeneity.

Indexed as

Dietary SupplementsDigestive System Surgical ProceduresNutritional StatusHumansLength of StayPerioperative CarePostoperative ComplicationsDigestive system surgical proceduresGastrointestinal neoplasmsNutritional supportPostoperative complications

Identifiers

PMID31062270
OpenAlexW2944540418

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.