Evidence map›Paper›PMID 31062232›Full record

ReviewThe journal of physiological sciences : JPS2019

Mild hyperbaric oxygen: mechanisms and effects.

Akihiko Ishihara

Abstract readReview
In one paragraph

Review in The journal of physiological sciences : JPS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Hyperoxia: Effective Mechanism of Hyperbaric Treatment at Mild-Pressure.International journal of molecular sciences · 2024
    Review
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  19. A Novel Strategy to Enhance Antioxidant Content inBioengineering (Basel, Switzerland) · 2023
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

1 author.

Akihiko IshiharaLaboratory of Cell Biology and Life Science, Graduate School of Human and Environmental Studies, Kyoto University, Sakyo-ku, Kyoto, 606-8501, Japan. ishihara.akihiko.8s@kyoto-u.ac.jp.ORCID http://orcid.org/0000-0003-3784-7857

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Adequate oxygen supply by exposure to mild hyperbaric oxygen at appropriately high atmospheric pressure (1266-1317 hPa) and increased oxygen concentration (35-40% oxygen) has a possibility of improving the oxidative metabolism in cells and tissues without barotrauma and excessive production of reactive oxygen species. Therefore, metabolic syndrome and lifestyle-related diseases, including type 2 diabetes and hypertension, in rats were inhibited and/or improved by exposure to mild hyperbaric oxygen. It accelerated the growth-induced increase in oxidative capacity of the skeletal muscle in rats and inhibited the age-related decrease in oxidative capacity of the skeletal muscle in mice. A decrease in dopaminergic neurons in the substantia nigra of mice with Parkinson's disease was inhibited by exposure to mild hyperbaric oxygen. This review describes the beneficial effects of exposure to mild hyperbaric oxygen on some metabolic diseases and their perspectives.

Indexed as

AnimalsHumansHyperbaric OxygenationMetabolic DiseasesMuscle, SkeletalOxidation-ReductionOxygenOxygenDissolved oxygenMild hyperbaric oxygenOxidative metabolism

Identifiers

PMID31062232
PMCPMC10717139

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.