Evidence map›Paper›PMID 31062177›Full record

ReviewJournal of medical toxicology : official journal of the American College of Medical Toxicology2019

Hydrogen Sulfide Toxicity: Mechanism of Action, Clinical Presentation, and Countermeasure Development.

Patrick C Ng, Tara B Hendry-Hofer, Alyssa E Witeof, Matthew Brenner, Sari B Mahon, Gerry R Boss, Philippe Haouzi, Vikhyat S Bebarta

Abstract readReview
In one paragraph

Review in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
5.7field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 115 citations in OpenAlex.

  1. Toxidromes.Nature reviews. Disease primers · 2026
    Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Hydrogen Sulfide (HInternational journal of molecular sciences · 2025
    Review
  10. CSE/HInternational journal of molecular sciences · 2025
    Review
  11. Review
  12. Review
  13. Signaling Paradigms of HAntioxidants (Basel, Switzerland) · 2024
    Review
  14. Article
  15. Article
  16. Article
  17. Novel HRSC advances · 2023
    Article
  18. Article
  19. Plants and Mushrooms as Possible New Sources of HInternational journal of molecular sciences · 2023
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 6 institutions in 1 country.

Patrick C NgDenver Health and Hospital Authority, Rocky Mountain Poison and Drug Center, Denver, CO, USA. patrick.ng@rmpdc.org.
Tara B Hendry-HoferDepartment of Emergency Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Alyssa E WiteofDepartment of Emergency Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.
Matthew BrennerBeckman Laser Institute and Medical Clinic, University of California, Irvine, CA, USA.
Sari B MahonBeckman Laser Institute and Medical Clinic, University of California, Irvine, CA, USA.
Gerry R BossDepartment of Medicine, University of California, San Diego, CA, USA.
Philippe HaouziDivision of Pulmonary and Critical Care Medicine, Department of Medicine, Pennsylvania State University, College of Medicine, Hershey, PA, USA.
Vikhyat S BebartaDenver Health and Hospital Authority, Rocky Mountain Poison and Drug Center, Denver, CO, USA.
University of California, Irvine · USUniversity of Colorado Anschutz Medical Campus · USHealth and Hospital Corporation · USPennsylvania State University · USUniversity of California, San Diego · USUniversity of Colorado Denver · US

Funding

Development of the Vitamin B12 Analog cobinamide as a Hydrogen Sulfide AntidoteU01NS087964 · NINDS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI BOSS, GERRY R · 2015 to 2019
$4.3M
Methylene blue as an antidote against hydrogen sulfide intoxicationU01NS097162 · NINDS · PENNSYLVANIA STATE UNIV HERSHEY MED CTR · PI HAOUZI, PHILIPPE A · 2016 to 2018
$2.2M
NINDS NIH HHS U01 NS087964NINDS NIH HHS U01 NS097162
6 · The paper itself

Abstract

introductionHydrogen sulfide (H DISCUSSION: In vivo, H

conclusionH

Indexed as

AntidotesChemically-Induced DisordersEnvironmental ExposureHumansHydrogen SulfideAntidotesHydrogen SulfideCountermeasureHydrogen sulfideMitochondrial toxinSulfide

Identifiers

PMID31062177
PMCPMC6825067
OpenAlexW2944756501

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.