Evidence map›Paper›PMID 31062168›Full record

ReviewCurrent HIV/AIDS reports2019

Role of T Lymphocytes in HIV Neuropathogenesis.

Caroline Subra, Lydie Trautmann

Open access · greenAbstract readReview
In one paragraph

Review in Current HIV/AIDS reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it, 37 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Unraveling the complexities of neurotropic virus infection and immune evasion.Microbiology and molecular biology reviews : MMBR · 2025
    Review
  9. Review
  10. Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Infectious Diseases.Advances in neurobiology · 2024
    Review
  18. Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Caroline SubraHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
Lydie TrautmannHenry M. Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. ltrautmann@hivresearch.org.
Henry M. Jackson Foundation · USWalter Reed Army Institute of Research · US

Funding

Critical Role of Cytotoxic T Cells in HIV NeuropathogenesisR01MH106466 · NIMH · OREGON HEALTH & SCIENCE UNIVERSITY · PI PICKER, LOUIS J., SPUDICH, SERENA S · 2016 to 2020
$2.8M
NIMH NIH HHS R01 MH106466
6 · The paper itself

Abstract

purpose of reviewThe purpose of this review is to summarize the current knowledge on the role of CD4 RECENT

findingsHIV targets the CNS early in infection, and HIV-infected individuals suffer from mild forms of neurological impairments even under antiretroviral therapy (ART). CD4

Indexed as

CD4-Positive T-LymphocytesCD8-Positive T-LymphocytesCentral Nervous SystemCytokinesHIV-1HIV InfectionsHumansMonocytesCytokinesCNS HIV invasionCNS inflammationHIV-infected cell killingHIV neuropathogenesisT lymphocytes

Identifiers

PMID31062168
PMCPMC6579685
OpenAlexW2944319459

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.