Evidence map›Paper›PMID 31062135›Full record

ArticleEuropean radiology2019

Differential diagnosis of pulmonary infections in immunocompromised patients using high-resolution computed tomography.

Yoshie Kunihiro, Nobuyuki Tanaka, Reo Kawano, Toshiaki Yujiri, Makoto Kubo, Kazuhiro Ueda, Toshikazu Gondo, Taiga Kobayashi, Tsuneo Matsumoto

Abstract read
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In one paragraph

Article in European radiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.9field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 39 citations in OpenAlex.

  1. Pre-Hematopoietic Stem Cell Transplantation Lung Computed Tomography as an Alternative to the Pulmonary Function Test during the COVID-19 Pandemic.Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation · 2020
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  11. Factors associated with pulmonary infection in kidney and kidney-pancreas transplant recipients: a case-control study.Jornal brasileiro de pneumologia : publicacao oficial da Sociedade Brasileira de Pneumologia e Tisilogia · 2023
    Article
  12. Article
  13. Review
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  15. Journal of fungi (Basel, Switzerland) · 2020
    Review
  16. Article
  17. Chitotriosidase: a marker and modulator of lung disease.European respiratory review : an official journal of the European Respiratory Society · 2020
    Review
  18. Article
  19. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Yoshie KunihiroDepartment of Radiology, National Hospital Organization Yamaguchi - Ube Medical Center, 685 Higashikiwa, Ube, Yamaguchi, 755-0241, Japan. kyoshie@yamaguchi-u.ac.jp.
Nobuyuki TanakaDepartment of Radiology, National Hospital Organization Yamaguchi - Ube Medical Center, 685 Higashikiwa, Ube, Yamaguchi, 755-0241, Japan.
Reo KawanoCenter for Integrated Medical Research, Hiroshima University Hospital, Kasumi 1-2-3 Minami-ku, Hiroshima, Hiroshima, 734-8551, Japan.
Toshiaki YujiriDivision of Endocrinology, Metabolism, Hematological Science and Therapeutics, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Makoto KuboDepartment of Medicine and Clinical Science, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Kazuhiro UedaDepartment of Surgery and Clinical Science, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Toshikazu GondoDivision of Pathology, Fujisawa City Hospital, 2-6-1 Fujisawa, Fujisawa, Kanagawa, 251-8550, Japan.
Taiga KobayashiDepartment of Radiology, Yamaguchi University Graduate School of Medicine, 1-1-1 Minamikogushi, Ube, Yamaguchi, 755-8505, Japan.
Tsuneo MatsumotoDepartment of Radiology, National Hospital Organization Yamaguchi - Ube Medical Center, 685 Higashikiwa, Ube, Yamaguchi, 755-0241, Japan.
Yamaguchi University · JPNational Sanyo Hospital · JPFujisawa City Hospital · JPHiroshima University Hospital · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThe aims of this study were to compare the high-resolution computed tomography (HRCT) findings of pulmonary infections in immunocompromised patients and to assess the usefulness of HRCT in the differential diagnosis of these infections.

methodsA total of 345 immunocompromised patients with pulmonary infections were included in this study. The diagnoses of the patients consisted of bacterial pneumonia (123 cases), pneumocystis pneumonia (PCP) (105 cases), fungal pneumonia (80 cases), tuberculosis (15 cases), cytomegalovirus pneumonia (11 cases), and septic embolism (11 cases). Two chest radiologists retrospectively evaluated the computed tomography (CT) images, which consisted of 22 findings including ground-glass attenuation, consolidation, nodules, and thickening of the bronchial wall and interlobular septum. Associations between the CT criteria and infections were investigated using χ

resultsBronchial wall thickening was a significant indicator for bacterial pneumonia (p = 0.002; odds ratio [OR], 2.341; 95% confidence interval [CI], 1.378-3.978). The presence of a mosaic pattern and the absence of nodules were significant indicators for PCP (p < 0.001; OR, 9.808; 95% CI, 4.883-13.699, and p < 0.001; OR, 6.834; 95% CI, 3.438-13.587, respectively). The presence of nodules was a significant indicator for fungal infection (p = 0.005; OR, 2.531; 95% CI, 1.326-4.828). The AUC for PCP was the highest (0.904).

conclusionsHRCT findings are potentially useful for the differential diagnosis of some pulmonary infections in immunocompromised patients. KEY POINTS: • Differential diagnosis of pulmonary infections in immunocompromised patients could be established with the help of high-resolution computed tomography. • Bronchial wall thickening was a significant indicator for bacterial pneumonia. • The presence of a mosaic pattern and the absence of nodules were significant indicators for pneumocystis pneumonia.

Indexed as

AlgorithmsImmunocompromised HostAdolescentAdultAgedAged, 80 and overChildChild, PreschoolDiagnosis, DifferentialFemaleHumansMaleMiddle AgedPneumonia, BacterialPneumonia, ViralRetrospective StudiesImmunocompromised hostMultivariate analysisPneumoniaX-ray computed tomography

Identifiers

PMID31062135
OpenAlexW2944541171

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.