Evidence map›Paper›PMID 31062057›Full record

ArticleWorld journal of surgery2019

Prophylactic Pancreatectomies Carry Prohibitive Mortality at Low-Volume Centers: A California Cancer Registry Study.

Ann Falor Callahan, Philip H G Ituarte, Leanne Goldstein, Susanne G Warner, Yanghee Woo, Gagandeep Singh, Yuman Fong, Laleh G Melstrom

Open access · greenAbstract read
In one paragraph

Article in World journal of surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
0.2field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it, 5 citations in OpenAlex.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ann Falor CallahanDepartment of Surgical Oncology, City of Hope National Medical Center, 1500 E Duarte Rd., Duarte, CA, 91010, USA.
Philip H G ItuarteDepartment of Biostatistics, City of Hope National Medical Center, Duarte, CA, USA.
Leanne GoldsteinDepartment of Biostatistics, City of Hope National Medical Center, Duarte, CA, USA.
Susanne G WarnerDepartment of Surgical Oncology, City of Hope National Medical Center, 1500 E Duarte Rd., Duarte, CA, 91010, USA.
Yanghee WooDepartment of Surgical Oncology, City of Hope National Medical Center, 1500 E Duarte Rd., Duarte, CA, 91010, USA.
Gagandeep SinghDepartment of Surgical Oncology, City of Hope National Medical Center, 1500 E Duarte Rd., Duarte, CA, 91010, USA.
Yuman FongDepartment of Surgical Oncology, City of Hope National Medical Center, 1500 E Duarte Rd., Duarte, CA, 91010, USA.
Laleh G MelstromDepartment of Surgical Oncology, City of Hope National Medical Center, 1500 E Duarte Rd., Duarte, CA, 91010, USA. lmelstrom@coh.org.
City Of Hope National Medical Center · US

Funding

Oncology Research Career Development ProgramK12CA001727 · NCI · CITY OF HOPE NATIONAL MEDICAL CENTER · PI MORTIMER, JOANNE E. · 1992 to 2024
$14.6M
Center for Strategic Scientific Initiatives, National Cancer Institute NIH 5K12CA001727-20NCI NIH HHS K12 CA001727
6 · The paper itself

Abstract

backgroundPancreatectomy for malignancy is associated with improved outcomes when performed at high-volume centers. The goal of this study was to assess pancreatectomy outcomes for premalignant cystic lesions as a function of hospital volume.

methodsThe Healthcare Cost and Utilization Project (HCUP) was queried for all pancreatectomies performed in California from 2003 to 2011. Cases were stratified, separating benign versus malignant disease. Hospitals were categorized as low-volume (≤25 pancreatectomies/year; LV) or high-volume (>25; HV) centers. Perioperative morbidity, mortality, and length of stay were compared in HV vs. LV centers.

resultsThere were 7554 pancreatectomies performed in 201 hospitals during the study period, where 5652 (75%) procedures were performed for malignancy, 338 (4%) for chronic pancreatitis, and 1564 (21%) for benign/premalignant cysts. The majority of pancreatectomies for cystic disease were performed at LV centers (65%). There were no significant differences in length of stay (7 vs. 8 days; p = 0.6) or 90-day readmission rates (12.8% vs. 12.9%; p = 1.0) in HV versus LV centers. However, there were higher surgical (46.2% LV vs. 41.1% HV, p = 0.05) and medical (13.3% LV vs. 9.2% HV; p = 0.017) complications at LV centers. Most importantly, there was a fourfold higher in-hospital mortality at LV centers (2.36% vs. 0.55%; p = 0.007).

conclusionPancreatic resection for benign lesions at HV hospitals is associated with significantly lower morbidity and mortality, suggesting that when feasible, patients should seek care at high-volume centers for these semi-elective surgeries.

Indexed as

Hospital MortalityHospitals, Low-VolumeRegistriesAdultAgedCaliforniaFemaleHospitals, High-VolumeHumansMaleMiddle AgedPancreatectomyPancreatic CystPancreatic NeoplasmsRetrospective Studies

Identifiers

PMID31062057
PMCPMC7519588
OpenAlexW2944203139

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.