Evidence map›Paper›PMID 31062010›Full record

ArticleChemical communications (Cambridge, England)2019

Ring opening of epoxides with [

Stefan Verhoog, Allen F Brooks, Wade P Winton, Benjamin L Viglianti, Melanie S Sanford, Peter J H Scott

Abstract read
In one paragraph

Article in Chemical communications (Cambridge, England), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Photoredox Nucleophilic (Radio)fluorination of Alkoxyamines.Journal of the American Chemical Society · 2024
    Article
  3. Article
  4. Article
  5. Closing the gap betweenEJNMMI radiopharmacy and chemistry · 2021
    Review
  6. A spot test for determination of residual TBA levels inAnalytical methods : advancing methods and applications · 2020
    Article
  7. Article
  8. Synthesis andRSC medicinal chemistry · 2020
    Article
  9. Synthesis of [Synthesis · 2019
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Stefan VerhoogDivision of Nuclear Medicine, Department of Radiology, The University of Michigan Medical School, Ann Arbor, Michigan 48109, USA. pjhscott@umich.edu.
Allen F Brooks
Wade P Winton
Benjamin L Viglianti
Melanie S Sanford
Peter J H Scott

Funding

Synthesis of Novel PET Radiotracers for Imaging in Alzheimer’s Disease and Related DisordersR01EB021155 · NIBIB · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI SANFORD, MELANIE S., SCOTT, PETER JAMES HENRY · 2016 to 2024
$3.2M
NIBIB NIH HHS R01 EB021155
6 · The paper itself

Abstract

A simple technique for the preparation of [18F]HF has been developed and applied to the generation of an [18F]FeF species for opening sterically hindered epoxides. This method has been successfully employed to prepare four drug-like molecules, including 5-[18F]fluoro-6-hydroxy-cholesterol, a potential adrenal/endocrine PET imaging agent. This easily automated one-pot procedure produces sterically hindered fluorohydrin PET imaging agents in good yields and high molar activities.

Indexed as

Positron-Emission TomographyEpoxy CompoundsFluoridesFluorine RadioisotopesHydrocarbons, FluorinatedIronRadiopharmaceuticalsEpoxy CompoundsFluoridesFluorine RadioisotopesHydrocarbons, FluorinatedIronRadiopharmaceuticals

Identifiers

PMID31062010
PMCPMC6542722

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.