Evidence map›Paper›PMID 31061988›Full record

ArticleACS applied bio materials2019

Stabilized Interleukin-4-Loaded Poly(lactic-

Alexis M Ziemba, Anthony R D'Amato, Taylor M MacEwen, Devan L Puhl, Abigail N Koppes, Ryan A Koppes, Michelle R Lennartz, Ryan J Gilbert

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied bio materials, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 17 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Alexis M ZiembaDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 Eighth Street, Troy, New York 12180, United States.ORCID 0000-0001-8947-9617
Anthony R D'AmatoDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 Eighth Street, Troy, New York 12180, United States.ORCID 0000-0002-8866-4180
Taylor M MacEwenDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 Eighth Street, Troy, New York 12180, United States.
Devan L PuhlDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 Eighth Street, Troy, New York 12180, United States.ORCID 0000-0002-8293-3415
Abigail N KoppesDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.ORCID 0000-0003-0433-9290
Ryan A KoppesDepartment of Chemical Engineering, Northeastern University, 360 Huntington Avenue, Boston, Massachusetts 02115, United States.ORCID 0000-0002-3376-6358
Michelle R LennartzCenter for Cell Biology and Cancer Research, Albany Medical College, 43 New Scotland Avenue, Albany, New York 12208, United States.ORCID 0000-0002-2519-8805
Ryan J GilbertDepartment of Biomedical Engineering, Rensselaer Polytechnic Institute, 110 Eighth Street, Troy, New York 12180, United States.ORCID 0000-0002-3501-6753
Rensselaer Polytechnic Institute · USNortheastern University · USAlbany Medical Center Hospital · US

Funding

Enhanced Neuroprotection Following Acute SCI Using Fibrous MaterialsR01NS092754 · NINDS · RENSSELAER POLYTECHNIC INSTITUTE · PI GILBERT, RYAN J. · 2015 to 2019
$1.3M
NINDS NIH HHS R01 NS092754
6 · The paper itself

Abstract

Macrophages are immune cells involved in wound healing and tissue regeneration; however, the sustained presence of proinflammatory macrophages in wound sites impairs healing. In this study, we shifted peritoneal macrophage polarization away from a proinflammatory (M1) phenotype through exposure to stabilized interleukin-4 (IL-4) in poly(lactic-

Indexed as

cytokine stabilizationinflammationinterleukin-4macrophagepoly(lactic-co-glycolic acid)

Identifiers

PMID31061988
PMCPMC6499395
OpenAlexW2917166851

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.