Evidence map›Paper›PMID 31061891›Full record

ArticleJGH open : an open access journal of gastroenterology and hepatology2019

Humoral response to

Gunnel Henriksson, Johan Bredberg, Marlene Wullt, Ebbe Lyrenäs, Ulf Hindorf, Björn Ohlsson, Olof Grip

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JGH open : an open access journal of gastroenterology and hepatology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.1field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Article
  3. Evaluation of anti-infective-relatedInternational journal of medical sciences · 2020
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 2 countries.

Gunnel HenrikssonDepartment of Laboratory Medicine Lund University Lund Sweden.ORCID https://orcid.org/0000-0003-4225-3439
Johan BredbergDepartment of Education, Østfold University College Halden Norway.
Marlene WulltDepartment of Clinical Sciences Malmö Lund University Malmö Sweden.
Ebbe LyrenäsDepartment of Gastroenterology Central Hospital Kristianstad Kristianstad Sweden.
Ulf HindorfDepartment of Gastroenterology Lund University Lund Sweden.
Björn OhlssonDepartment of Surgery Blekinge Hospital Karlshamn Sweden.
Olof GripDepartment of Clinical Sciences Malmö Lund University Malmö Sweden.
Lund University · SEBlekingesjukhuset · SEKristianstad University · SEØstfold University College · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BACKGROUND AND

aimAn abnormal immune response to intestinal bacteria has been observed in Crohn's disease (CD).

methodsA total of 71 consecutive outpatients with CD, 67 with ulcerative colitis (UC), and 121 healthy controls were analyzed for serum IgA and IgG to C. difficile toxins A and B.

resultsIgA levels were similar in all study groups. IgG to toxin A was increased similarly in CD and UC (

conclusionOur findings add support to the idea of a disturbed interaction between intestinal cells and the microbiota being part of the CD disease mechanism. An abnormal immune response to C. difficile toxin B may be a critical component of this interaction.

Indexed as

Clostridium difficileClostridium difficile toxin BCrohn's diseasehumoral responseinflammatory bowel disease

Identifiers

PMID31061891
PMCPMC6487827
OpenAlexW2908045388

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.