Evidence map›Paper›PMID 31061822›Full record

Trial reportBioMed research international2019

Pentraxin 3 Detects Clinically Significant Fibrosis in Patients with Chronic Viral Hepatitis C.

Joanna Gorka-Dynysiewicz, Monika Pazgan-Simon, Jolanta Zuwala-Jagiello

Open access · hybridAbstract readClinical Trial
PubMed Full text at PMC Publisher
In one paragraph

Trial report in BioMed research international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Review
  5. Article
  6. Article
  7. Observational
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Joanna Gorka-DynysiewiczDepartment of Pharmaceutical Biochemistry, Wroclaw Medical University, Poland.ORCID 0000-0003-1797-025X
Monika Pazgan-SimonDepartment of Infectious Diseases and Hepatology, Wroclaw Medical University, Poland.
Jolanta Zuwala-JagielloDepartment of Pharmaceutical Biochemistry, Wroclaw Medical University, Poland.
Wroclaw Medical University · PL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Pentraxin 3 (PTX3) plays a pathogenic role in experimental models of chronic liver injury and contributes to the progression of fibrosis. The detection of advanced fibrosis (METAVIR F≥3) is important to identify patients who are in urgent need of antiviral treatments

Indexed as

AdolescentAdultAgedAntiviral AgentsAspartate AminotransferasesBiomarkersC-Reactive ProteinElasticity Imaging TechniquesFemalegamma-GlutamyltransferaseHepatitis C, ChronicHumansLiverLiver CirrhosisMaleMiddle AgedAntiviral AgentsAspartate AminotransferasesBiomarkersC-Reactive Proteingamma-GlutamyltransferasePentraxinsSerum Amyloid P-ComponentTGFB1 protein, humanTransforming Growth Factor beta1

Identifiers

PMID31061822
PMCPMC6466943
OpenAlexW2928214279

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.