Evidence map›Paper›PMID 31061791›Full record

ArticleLeukemia research reports2019

A rare case of near-haploid acute lymphoblastic leukemia.

William Gonzalez-Marques, Ann-Leslie Zaslav, Dhana Balakrishnan, Laura Hogan, Yupo Ma, Daniel Tully, Paula Fernicola, Roxana Ponce, Htien Lee, Theresa Mercado and 1 more

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PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia research reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

William Gonzalez-MarquesStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Ann-Leslie ZaslavStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Dhana BalakrishnanStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Laura HoganStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Yupo MaStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Daniel TullyStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Paula FernicolaStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Roxana PonceStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Htien LeeStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Theresa MercadoStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.
Tahmeena AhmedStony Brook University Medical Center, Department of Pathology, Room 3-523, 101 Nicolls Road, Stony Brook, New York 11794-7300, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Near-haploid acute lymphoblastic leukemia is seen in <1% of cases and carries an unfavorable prognosis. We report a case in an 18-year old male. He presented with two abnormal clones, one with 27-28 and one with 54-56 chromosomes. Near-haploidy (27-28) carries a poor prognosis and hyperdiploidy (>50) has a good prognosis. The correct diagnosis was critical for this patient's prognosis and treatment. The patient achieved remission after a bone marrow transplant from a 10/10 HLA matched sibling donor. He relapsed six months later and expired seven months later. This case illustrates the need for careful standard and molecular cytogenetic analysis for accurate diagnosis and treatment for this rare type of ALL.

Indexed as

Acute lymphoblastic leukemiaCytogeneticsHyperdiploidHypodiploidNear-haploid ALL

Identifiers

PMID31061791
PMCPMC6488524

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.