ArticleBiomedical optics express2019
Computational structured illumination for high-content fluorescence and phase microscopy.
Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
11 citing papers in PubMed.
- Article
- Maskless and on-chip LED-array microscope with spatially-varying angle calibration for centimeter-scale phase imaging.bioRxiv : the preprint server for biology · 2025Article
- Recover Biological Structure from Sparse-View Diffraction Images with Neural Volumetric Prior.Proceedings. IEEE International Conference on Computer Vision · 2025Article
- Stochastically structured illumination microscopy scan less super resolution imaging.Npj imaging · 2024Article
- Polarization differential interference contrast microscopy with physics-inspired plug-and-play denoiser for single-shot high-performance quantitative phase imaging.Biomedical optics express · 2023Article
- Optical ptychography for biomedical imaging: recent progress and future directions [Invited].Biomedical optics express · 2023Review
- Three-dimensional bi-functional refractive index and fluorescence microscopy (BRIEF).Biomedical optics express · 2022Article
- High-Throughput, Label-Free and Slide-Free Histological Imaging by Computational Microscopy and Unsupervised Learning.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2022Article
- Review of bio-optical imaging systems with a high space-bandwidth product.Advanced photonics · 2021Article
- Super-resolution structured illumination microscopy: past, present and future.Philosophical transactions. Series A, Mathematical, physical, and engineering sciences · 2021Article
- Speckle-structured illumination for 3D phase and fluorescence computational microscopy.Biomedical optics express · 2019Article
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
High-content biological microscopy targets high-resolution imaging across large fields-of-view (FOVs). Recent works have demonstrated that computational imaging can provide efficient solutions for high-content microscopy. Here, we use speckle structured illumination microscopy (SIM) as a robust and cost-effective solution for high-content fluorescence microscopy with simultaneous high-content quantitative phase (QP). This multi-modal compatibility is essential for studies requiring cross-correlative biological analysis. Our method uses laterally-translated Scotch tape to generate high-resolution speckle illumination patterns across a large FOV. Custom optimization algorithms then jointly reconstruct the sample's super-resolution fluorescent (incoherent) and QP (coherent) distributions, while digitally correcting for system imperfections such as unknown speckle illumination patterns, system aberrations and pattern translations. Beyond previous linear SIM works, we achieve resolution gains of 4× the objective's diffraction-limited native resolution, resulting in 700 nm fluorescence and 1.2
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.