Evidence map›Paper›PMID 31061763›Full record

ArticleBiomedical optics express2019

Transverse chromatic offsets with pupil displacements in the human eye: sources of variability and methods for real-time correction.

Alexandra E Boehm, Claudio M Privitera, Brian P Schmidt, Austin Roorda

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Patches of Dysflective Cones in Eyes With No Known Disease.Investigative ophthalmology & visual science · 2022
    Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Alexandra E BoehmVision Science Graduate Group, University of California, Berkeley; Berkeley, CA 94720, USA.
Claudio M PriviteraSchool of Optometry, University of California, Berkeley; Berkeley, CA 94720, USA.
Brian P SchmidtVision Science Graduate Group, University of California, Berkeley; Berkeley, CA 94720, USA.
Austin RoordaVision Science Graduate Group, University of California, Berkeley; Berkeley, CA 94720, USA.

Funding

Advanced Technology to Study Visual Function on a Cellular ScaleR01EY023591 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI DUNCAN, JACQUE LYNNE, ROORDA, AUSTIN · 2014 to 2023
$11.2M
From cone classes to ganglion cell types to color perception in peripheral visionR21EY024444 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI KLEIN, STANLEY A · 2015 to 2016
$431k
Dissecting color and spatial vision on a cellular scale in the human retinaF32EY027637 · NEI · UNIVERSITY OF CALIFORNIA BERKELEY · PI SCHMIDT, BRIAN PATRICK · 2017 to 2018
$116k
NEI NIH HHS F32 EY027637NEI NIH HHS R01 EY023591NEI NIH HHS R21 EY024444
6 · The paper itself

Abstract

Tracking SLO systems equipped to perform retinally targeted stimulus delivery typically use near-IR wavelengths for retinal imaging and eye tracking and visible wavelengths for stimulation. The lateral offsets between wavelengths caused by transverse chromatic aberration (TCA) must be carefully corrected in order to deliver targeted stimuli to the correct location on the retina. However, both the magnitude and direction of the TCA offset is dependent on the position of the eye's pupil relative to the incoming beam, and thus can change dynamically within an experimental session without proper control of the pupil position. The goals of this study were twofold: 1) To assess sources of variability in TCA alignments as a function of pupil displacements in an SLO and 2) To demonstrate a novel method for real-time correction of chromatic offsets. To summarize, we found substantial between- and within-subject variability in TCA in the presence of monochromatic aberrations. When adaptive optics was used to fully correct for monochromatic aberrations, variability both within and between observers was minimized. In a second experiment, we demonstrate that pupil tracking can be used to update stimulus delivery in the SLO in real time to correct for variability in chromatic offsets with pupil displacements.

Identifiers

PMID31061763
PMCPMC6484992

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.