Evidence map›Paper›PMID 31061759›Full record

ArticleBiomedical optics express2019

Robust deep learning method for choroidal vessel segmentation on swept source optical coherence tomography images.

Xiaoxiao Liu, Lei Bi, Yupeng Xu, Dagan Feng, Jinman Kim, Xun Xu

Abstract read
In one paragraph

Article in Biomedical optics express, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

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  15. Artificial intelligence in OCT angiography.Progress in retinal and eye research · 2021
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoxiao LiuDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Lei BiBiomedical and Multimedia Information Technology (BMIT) Research Group, The University of Sydney, Sydney, NSW, 2006, Australia.
Yupeng XuDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.
Dagan FengShanghai Key Laboratory of Fundus Disease, Shanghai Engineering Center for Visual Science and Photomedicine, Shanghai, 200080, China.
Jinman KimBiomedical and Multimedia Information Technology (BMIT) Research Group, The University of Sydney, Sydney, NSW, 2006, Australia.
Xun XuDepartment of Ophthalmology, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, 200080, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Accurate choroidal vessel segmentation with swept-source optical coherence tomography (SS-OCT) images provide unprecedented quantitative analysis towards the understanding of choroid-related diseases. Motivated by the leading segmentation performance in medical images from the use of deep learning methods, in this study, we proposed the adoption of a deep learning method, RefineNet, to segment the choroidal vessels from SS-OCT images. We quantitatively evaluated the RefineNet on 40 SS-OCT images consisting of ~3,900 manually annotated choroidal vessels regions. We achieved a segmentation agreement (SA) of 0.840 ± 0.035 with clinician 1 (C1) and 0.823 ± 0.027 with clinician 2 (C2). These results were higher than inter-observer variability measure in SA between C1 and C2 of 0.821 ± 0.037. Our results demonstrated that the choroidal vessels from SS-OCT can be automatically segmented using a deep learning method and thus provided a new approach towards an objective and reproducible quantitative analysis of vessel regions.

Identifiers

PMID31061759
PMCPMC6485000

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.