ReviewClinics in colon and rectal surgery2019
Operative Management of Anastomotic Leaks after Colorectal Surgery.
Review in Clinics in colon and rectal surgery, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 35 citations in OpenAlex.
- The role of remote ischaemic preconditioning (RIPC) in colorectal surgery: a meta-analysis of randomized-controlled studies.Langenbeck's archives of surgery · 2025Pooled it
- Abdominoperineal pull-through with delayed coloanal anastomosis for pelvic anastomotic failure-a systematic review.Techniques in coloproctology · 2025Pooled it
- ArtiSential® vs. straight-stick in laparoscopic left-sided colorectal resection: a prospective randomized study.Surgical endoscopy · 2026Trial
- Prevention, Recognition, and Management of Anastomotic Leakage and Pelvic Sepsis After Rectal Cancer Surgery: A Structured Narrative Review.Journal of clinical medicine · 2026Review
- Prevention and management of anastomotic leakage after colorectal resection: evolving trends among Italian surgeons. A SICCR survey.Updates in surgery · 2026Article
- Updates in surgery for colorectal cancer: incidence and risk factors for acute anastomotic leak-a retrospective study.Updates in surgery · 2026Article
- Left internal iliac artery stenosis as a risk factor for anastomotic leakage after left-sided colorectal surgery.Frontiers in surgery · 2026Article
- The effect of neoadjuvant chemoradiotherapy on perioperative outcomes in rectal cancer patients following stoma reversal-a retrospective cohort analysis.Journal of gastrointestinal oncology · 2025Article
- Determinants of surgical management outcomes among adult patients with intestinal obstruction at Mzuzu central hospital, Malawi.BMC surgery · 2025Article
- Article
- Comparative Risk of Complications Following Intestinal Surgery After Infliximab, Vedolizumab, or Ustekinumab Treatment: Systematic Review & Meta-Analysis.Pharmaceuticals (Basel, Switzerland) · 2025Review
- The gut barrier as a gatekeeper in colorectal cancer treatment.Oncotarget · 2024Review
- Validation of an endoscopic anastomotic grading score as an intraoperative method for assessing stapled rectal anastomoses.Techniques in coloproctology · 2023Article
- The impact of sarcopenia on the postoperative outcome in colorectal cancer surgery.Medicine and pharmacy reports · 2023Review
- Fully covered self-expandable metal stent placed over a stapled colon anastomosis in an animal model: A pilot study of colon metabolism over the stent.JGH open : an open access journal of gastroenterology and hepatology · 2022Article
- Laparoscopic redo anastomosis for management of intraperitoneal anastomotic leakage after colonic surgery.BMC surgery · 2022Article
- Ileocolic anastomosis after right hemicolectomy: stapled end-to-side, stapled side-to-side, or handsewn?International journal of colorectal disease · 2022Article
- Use of right colon vaginoplasty in gender affirming surgery: proposed advantages, review of technique, and outcomes.Surgical endoscopy · 2021Review
- Increased mortality and altered local immune response in secondary peritonitis after previous visceral operations in mice.Scientific reports · 2021Article
- Management and 1-year outcomes of anastomotic leakage after elective colorectal surgery.International journal of colorectal disease · 2021Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anastomotic leak is associated with increased morbidity and mortality after colorectal surgery. Although surgical techniques have improved over time, anastomotic leak is still a reality in colorectal surgery with rates ranging from as low as 1% for low-risk anastomoses, such as enteroenteric or ileocolic, to 19% for high-risk coloanal anastomoses. There are many varied risk factors for anastomotic leak. However, many of the risk factors have not been definitively proven in high-quality studies. Presumably, risk factors are cumulative and every effort should be made to optimize modifiable risk factors in the perioperative period. Treatment of anastomotic leak should start with the determination of patient stability followed by resuscitation and diagnostic imaging or operative exploration. Operative findings will dictate surgical approach with the goal of controlling sepsis and stabilizing the patient. If nonoperative treatment is undertaken, close patient monitoring is necessary to ensure control of sepsis and that intervention is undertaken if the clinical picture changes. Early intervention at each stage is key to decreasing the morbidity of anastomotic leak.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.