Evidence map›Paper›PMID 31061530›Full record

ArticleNature immunology2019

Membrane metalloprotease TRABD2A restricts HIV-1 progeny production in resting CD4

Guoxin Liang, Li Zhao, Ying Qiao, Wenqing Geng, Xiaowei Zhang, Mei Liu, Jinxiu Dong, Haibo Ding, Hong Sun, Hong Shang

Erratum issuedAbstract read
PubMed Publisher
In one paragraph

Article in Nature immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.4field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 24 citations in OpenAlex.

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  8. Urokinase plasminogen activator surface receptor restricts HIV-1 replication by blocking virion release from the cell membrane.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  9. Article
  10. Article
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  12. Neuropilin-1, a myeloid cell-specific protein, is an inhibitor of HIV-1 infectivity.Proceedings of the National Academy of Sciences of the United States of America · 2022
    Article
  13. Article
  14. Article
  15. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Guoxin LiangKey Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, China. gxliang@cmu.edu.cn.ORCID http://orcid.org/0000-0003-1789-9094
Li ZhaoKey Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, China.
Ying QiaoThe Core Laboratory for Public Health Science and Practice, The First Affiliated Hospital, China Medical University, Shenyang, China.
Wenqing GengKey Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, China.
Xiaowei ZhangThe Core Laboratory for Public Health Science and Practice, The First Affiliated Hospital, China Medical University, Shenyang, China.
Mei LiuKey Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, China.
Jinxiu DongKey Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, China.
Haibo DingKey Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, China.
Hong SunKey Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, China.
Hong ShangKey Laboratory of AIDS Immunology of National Health and Family Planning Commission, Department of Laboratory Medicine, The First Affiliated Hospital, China Medical University, Shenyang, China. hshang@cmu.edu.cn.ORCID http://orcid.org/0000-0001-5333-8943
Chinese Academy of Medical Sciences & Peking Union Medical College · CNFirst Hospital of China Medical University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Resting CD4

Indexed as

Virus ReplicationAnimalsCationsCD4-Positive T-LymphocytesCell LineEnzyme Activationgag Gene Products, Human Immunodeficiency VirusGene ExpressionHIV-1HIV InfectionsHost-Pathogen InteractionsHumansMembrane ProteinsMetalloproteasesMultigene FamilyProteolysisCationsgag Gene Products, Human Immunodeficiency VirusMembrane ProteinsMetalloproteasesSAM Domain and HD Domain-Containing Protein 1

Identifiers

PMID31061530
OpenAlexW2943545292

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.