ArticleBritish journal of cancer2019
Prediabetes and diabetes in relation to risk of gastric adenocarcinoma.
Article in British journal of cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Diabetes History and Gastric Cancer Risk: Different Results by Types of Follow-Up Studies.Asian Pacific journal of cancer prevention : APJCP · 2022Pooled it
- The association between diabetes and gastric cancer: results from the Stomach Cancer Pooling Project Consortium.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2022Pooled it
- Associations between Diabetes Mellitus and Selected Cancers.International journal of molecular sciences · 2024Review
- Incident Cancer Risk in Patients with Incident Type 2 Diabetes Mellitus in Hungary (Part 1).Cancers · 2024Article
- Increased risk of cancer and cancer-related mortality in middle-aged Korean women with prediabetes and diabetes: a population-based study.Epidemiology and health · 2023Article
- Diabetes Mellitus and Gastric Cancer: Correlation and Potential Mechanisms.Journal of diabetes research · 2023Review
- [Diabetes mellitus and cancer: a system of insulin-like growth factors].Problemy endokrinologii · 2021Article
- The Relationship between Diabetes Mellitus and Gastric Cancer and the Potential Benefits of Metformin: An Extensive Review of the Literature.Biomolecules · 2021Review
- Proteomics Analysis of Gastric Cancer Patients with Diabetes Mellitus.Journal of clinical medicine · 2021Article
- Glucose Intolerance and Cancer Risk: A Community-Based Prospective Cohort Study in Shanghai, China.Frontiers in oncology · 2021Article
- Metformin use and risk of gastric adenocarcinoma in a Swedish population-based cohort study.British journal of cancer · 2019Article
- Feasibility of ERAS in Patients With Gastric Cancer Complicated by Diabetes Mellitus.Technology in cancer research & treatmentReview
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhether prediabetes or diabetes increases the risk of gastric adenocarcinoma is not clear.
methodsThis cohort study included 111,198 participants in the Northern Swedish Health and Disease Study. The participants were followed up from November 1985 to April 2017. The exposure to prediabetes or diabetes was assessed by oral glucose tolerance tests and self-reports. The incidence of the outcome gastric adenocarcinoma was identified from the Swedish Cancer Registry. Multivariable Cox regressions were used to analyse the associations between prediabetes or diabetes and the risk of gastric adenocarcinoma, providing hazard ratios (HR) with 95% confidence intervals (CI), with adjustment for sex, age, calendar year, body mass index, tobacco smoking and education level.
resultsCompared with normoglycaemic participants, the risk of gastric adenocarcinoma was not increased among participants with prediabetes (HR 1.07, 95% CI 0.79-1.44), diabetes (HR 0.77, 95% CI 0.46-1.29) or any of these exposures (HR 0.96, 95% CI 0.73-1.27). No associations were identified between prediabetes or diabetes and the risk of gastric adenocarcinoma in stratified analyses or in analyses separating cardia and non-cardia gastric adenocarcinoma.
conclusionsThis study does not support the hypothesis that prediabetes or diabetes increases the risk of gastric adenocarcinoma.
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