Evidence map›Paper›PMID 31061428›Full record

ArticleScientific reports2019

A Fully-Flexible Solution-Processed Autonomous Glucose Indicator.

Jonathan D Yuen, Ankit Baingane, Qumrul Hasan, Lisa C Shriver-Lake, Scott A Walper, Daniel Zabetakis, Joyce C Breger, David A Stenger, Gymama Slaughter

Abstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. mmW Rotman Lens-Based Sensing: An Investigation Study.Sensors (Basel, Switzerland) · 2021
    Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jonathan D YuenCenter for Bio-Molecular Science and Engineering, U.S. Naval Research Laboratory, Washington, DC, 20375, USA.ORCID http://orcid.org/0000-0002-3713-5983
Ankit BainganeFrank Reidy Research Center for Bioelectrics and Department of Electrical & Computer Engineering, Old Dominion University, Norfolk, VA, 23529, USA.
Qumrul HasanFrank Reidy Research Center for Bioelectrics and Department of Electrical & Computer Engineering, Old Dominion University, Norfolk, VA, 23529, USA.
Lisa C Shriver-LakeCenter for Bio-Molecular Science and Engineering, U.S. Naval Research Laboratory, Washington, DC, 20375, USA.ORCID http://orcid.org/0000-0002-9894-6640
Scott A WalperCenter for Bio-Molecular Science and Engineering, U.S. Naval Research Laboratory, Washington, DC, 20375, USA.
Daniel ZabetakisCenter for Bio-Molecular Science and Engineering, U.S. Naval Research Laboratory, Washington, DC, 20375, USA.
Joyce C BregerCenter for Bio-Molecular Science and Engineering, U.S. Naval Research Laboratory, Washington, DC, 20375, USA.
David A StengerCenter for Bio-Molecular Science and Engineering, U.S. Naval Research Laboratory, Washington, DC, 20375, USA.
Gymama SlaughterFrank Reidy Research Center for Bioelectrics and Department of Electrical & Computer Engineering, Old Dominion University, Norfolk, VA, 23529, USA. gslaught@odu.edu.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the first demonstration of a fully-flexible, self-powered glucose indicator system that synergizes two flexible electronic technologies: a flexible self-powering unit in the form of a biofuel cell, with a flexible electronic device - a circuit-board decal fabricated with biocompatible microbial nanocellulose. Our proof-of-concept device, comprising an enzymatic glucose fuel cell, glucose sensor and a LED indicator, does not require additional electronic equipment for detection or verification; and the entire structure collapses into a microns-thin, self-adhering, single-centimeter-square decal, weighing less than 40 mg. The flexible glucose indicator system continuously operates a light emitting diode (LED) through a capacitive charge/discharge cycle, which is directly correlated to the glucose concentration. Our indicator was shown to operate at high sensitivity within a linear glucose concentration range of 1 mM-45 mM glucose continuously, achieving a 1.8 VDC output from a flexible indicator system that deliver sufficient power to drive an LED circuit. Importantly, the results presented provide a basis upon which further development of indicator systems with biocompatible diffusing polymers to act as buffering diffusion barriers, thereby allowing them to be potentially useful for low-cost, direct-line-of-sight applications in medicine, husbandry, agriculture, and the food and beverage industries.

Identifiers

PMID31061428
PMCPMC6502809

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.