Evidence map›Paper›PMID 31061154›Full record

ArticleAntimicrobial agents and chemotherapy2019

Trends in and Predictors of Carbapenem Consumption across North American Hospitals: Results from a Multicenter Survey by the MAD-ID Research Network.

Nathaniel J Rhodes, Jamie L Wagner, Susan L Davis, John A Bosso, Debra A Goff, Michael J Rybak, Marc H Scheetz, MAD-ID Research Network

Registry-linked trialAbstract readMulticenter Study
In one paragraph

Article in Antimicrobial agents and chemotherapy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07096310 (Comparison Between Carbapenems and Noncarbapenem Broad Spectrum Beta-lactam Antibiotics as Initial Antibiotic Therapy Against Sepsis in Burn Patients), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07096310 phase1 / phase2active not recruitingnot on this mapstarted 2024, after this paper: background citation

Comparison Between Carbapenems and Noncarbapenem Broad Spectrum Beta-lactam Antibiotics as Initial Antibiotic Therapy Against Sepsis in Burn Patients: A Prospective Study

TypeinterventionalSponsorAin Shams UniversityRan2024 to 2026Enrolled400ConditionsSepsisArmsMeropenem I.V. 2g as a 3 hour infusion every 8 hours, Tazocin (pipercillin/tazobactam)
3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Article
  6. Epidemiology ofAntibiotics (Basel, Switzerland) · 2022
    Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Nathaniel J RhodesDepartment of Pharmacy Practice, Pharmacometrics Center of Excellence, Midwestern University Chicago College of Pharmacy, Downers Grove, Illinois, USA nrhode@midwestern.edu.ORCID 0000-0002-0018-5434
Jamie L WagnerDepartment of Pharmacy Practice, University of Mississippi School of Pharmacy, Jackson, Mississippi, USA.
Susan L DavisAnti-infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.
John A BossoDepartment of Clinical Pharmacy and Outcome Sciences, Medical University of South Carolina College of Pharmacy, Charleston, South Carolina, USA.
Debra A GoffDepartment of Pharmacy, The Ohio State University Wexner Medical Center, Columbus, Ohio, USA.
Michael J RybakAnti-infective Research Laboratory, Department of Pharmacy Practice, Eugene Applebaum College of Pharmacy and Health Sciences, Wayne State University, Detroit, Michigan, USA.
Marc H ScheetzDepartment of Pharmacy Practice, Pharmacometrics Center of Excellence, Midwestern University Chicago College of Pharmacy, Downers Grove, Illinois, USA.ORCID 0000-0002-1091-6130
MAD-ID Research Network

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We sought to define trends in and predictors of carbapenem consumption across community, teaching, and university-affiliated hospitals in the United States and Canada. We conducted a retrospective multicenter survey of carbapenem and broad-spectrum noncarbapenem beta-lactam consumption between January 2011 and December 2013. Consumption was tabulated as defined daily doses (DDD) or as days of therapy (DOT) per 1,000 patient days (PD). Multivariate mixed-effects models were explored, and final model goodness of fit was assessed by regressions of observed versus predicted values and residual distributions. A total of 20 acute-care hospitals responded. The centers treated adult patients (

Indexed as

Anti-Bacterial AgentsCanadaCarbapenemsDrug UtilizationHospitalsHumansMicrobial Sensitivity TestsMultivariate AnalysisSurveys and QuestionnairesUnited StatesAnti-Bacterial AgentsCarbapenemsantimicrobial stewardshipbeta-lactamsconsumptionepidemiologypharmacoeconometrics

Identifiers

PMID31061154
PMCPMC6591614

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.